ABSTRACT Background The existing diagnostic criteria for cancer cachexia do not meet clinical needs. We aimed to establish novel comprehensive evaluation scales for cachexia specific to patients with solid tumours. Methods This study included 12 651 patients (males: 6793 [53.7%]; females: 5858 [46.3%]; medium age: 58 [interquartile range:50/66] years ...
Chunlei Hu+25 more
wiley +1 more source
The pneumococcal bacteriocin streptococcin B is produced as part of the early competence cascade and promotes intraspecies competition. [PDF]
Richardson JD+4 more
europepmc +1 more source
Systemic Hormonal Contraceptive Use and Rhinitis Among Adult Women: An All of Us Database Analysis
Our study investigated the association between rhinitis, both allergic and nonallergic, and systemic hormonal contraceptive use among adult women aged 20–40 using a large national United States data set. We found that systemic hormonal contraceptive use was associated with allergic rhinitis but was not associated with nonallergic rhinitis.
Richard G. Chiu+6 more
wiley +1 more source
Abstract While members of large paralogous protein families share structural features, their functional niches often diverge significantly. Serine protease inhibitors (SERPINs), whose members typically function as covalent inhibitors of serine proteases, are one such family.
Laura M. Haynes+4 more
wiley +1 more source
ABSTRACT Pulmonary arterial hypertension (PAH) is a heterogenic diagnosis including idiopathic and hereditary PAH (IPAH/HPAH) and groups associated to connective tissue disease (APAH‐CTD) and congenital heart disease (APAH‐CHD). Pre‐ and post‐diagnosis societal costs in PAH subgroups are not well known.
Barbro Kjellström+4 more
wiley +1 more source
High Thermoelectric Performance of Flexible and Free-Standing Composite Films Enabled by 3D Inorganic Ag<sub>2</sub>Se Conductive Networks Filled with Organic PVDF. [PDF]
Xu Z, Hu Y, Hu Y, Xiao X, Yao Q.
europepmc +1 more source
The quorum sensing regulated sRNA Lrs1 participates in the adaptation of Pseudomonas aeruginosa in low iron by downregulating the siderophore pyochelin, the Quorum Sensing system PQS, and its associated virulence factor phenazines. ABSTRACT Iron is an essential nutrient for microbial growth. The opportunistic pathogen Pseudomonas aeruginosa can survive
Dimitra Panagiotopoulou+7 more
wiley +1 more source
Untypical tuneable emission activated by NIR radiation observed in gadolinium borate nanomaterials doped with Yb3+, Ho3+ and Ce3+ ions. [PDF]
Szczeszak A, Czajka J.
europepmc +1 more source
YOLO‐Behaviour: A simple, flexible framework to automatically quantify animal behaviours from videos
Abstract Manually coding behaviours from videos is essential to study animal behaviour but it is labour‐intensive and susceptible to inter‐rater bias and reliability issues. Recent developments of computer vision tools enable the automatic quantification of behaviours, supplementing or even replacing manual annotation.
Alex Hoi Hang Chan+13 more
wiley +1 more source
CD34+CD38- leukemia stem cells predict clinical outcomes in acute myeloid leukemia patients treated non-intensively with hypomethylating agents. [PDF]
Reuvekamp T+20 more
europepmc +1 more source