Results 61 to 70 of about 365,201 (273)

The sequence at Spike S1/S2 site enables cleavage by furin and phospho-regulation in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV

open access: yesScientific Reports, 2020
The Spike protein of the novel coronavirus SARS-CoV2 contains an insertion 680SPRRAR↓SV687 forming a cleavage motif RxxR for furin-like enzymes at the boundary of S1/S2 subunits. Cleavage at S1/S2 is important for efficient viral entry into target cells.
Mihkel Örd, I. Faustova, M. Loog
semanticscholar   +1 more source

Analysis of the Carrying City of Agricultural Land for Rice Crop in the Watershed of Beh, Nusa Tenggara Barat, Indonesia [PDF]

open access: yes
This research aims to analyze the carrying capacity of agricultural land for food self-sufficiency in the Beh Watershed, Sumbawa, West Nusa Tenggara, Indonesia. The research method used is a survey method and secondary data collection.
Herlina, Endah   +2 more
core   +2 more sources

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin   +9 more
wiley   +1 more source

Powdery mildew susceptibility of spring wheat cultivars as a major constraint on grain yield

open access: yesAnnals of Agricultural Sciences, 2019
Powdery mildew infection caused by Blumeria graminis f. sp. tritici and grain yield of 23 spring wheat cultivars were investigated under controlled and natural conditions during two growing seasons (2016/17 and 2017/18).
Ibrahim Sobhy Draz   +3 more
doaj   +1 more source

Understanding COVID-19 Vaccine Hesitancy in Nigeria Through University Community Lens [PDF]

open access: yes
It is widely acknowledged that vaccination represents one of the greatest advances in public health in human history. Nonetheless, vaccine rejection or hesitancy is a public health issue that has continuously thwarted coordinated attempts by health ...
Madu, Cajethan Okechukwu
core   +2 more sources

Improving optical access, sampling speed, and resolution for in vivo multiphoton microscopy [PDF]

open access: yes, 2020
Multiphoton microscopy is a powerful optical imaging modality renowned for its non-invasive nature and relatively affordable characteristics. In particular, it has found its niche in neuroimaging due to its ability to probe in vivo biological processes ...
Hassan, Ahmed Moustafa
core   +1 more source

Organization of the Proteostasis Network of Membraneless Organelles

open access: yesAdvanced Science, EarlyView.
A comprehensive mapping of the proteostasis network (PN) across membraneless organelles (MLOs) reveals how central PN components coordinate MLO regulation. The analysis uncovers principles of specificity and promiscuity within the PN. The findings suggest that HSP70 chaperones act as generic MLO regulators, while client specific HSP70 co‐chaperones may
Christine M. Lim   +6 more
wiley   +1 more source

Salix lapponum L. (Downy willow) in stands under anthropopressure in the Łęczna-Włodawa Lakeland

open access: yesActa Agrobotanica, 2012
The studies carried out in the years 2004-2005 and in 2009 were aimed at identifying the functioning conditions of a boreal plant relict, Salix lapponum, in its stands under anthropopressure in the Łęczna-Włodawa Lakeland.
Magdalena Pogorzelec
doaj   +1 more source

Abiotic Factors and Plant Communities Shape the Distribution of Soil Pathogenic Oomycetes in Chinese Grasslands

open access: yesAdvanced Science, EarlyView.
The continental‐scale study reveals that soil phosphorus strongly predicts the richness of soil pathogenic oomycetes in Chinese grasslands, while precipitation and plant species richness drive their absolute abundance; modeling predicts ≈42% of grassland areas may face elevated oomycete disease risk under future climate scenarios, especially in typical
Junsheng Ke   +10 more
wiley   +1 more source

Structure of floral nectaries, nectar production and sugar composition in nectar of 7 species of Vicia L. Fabaceae

open access: yesActa Agrobotanica, 2013
Nectaries of investigated species of Vicia were ranked into 3 morphological types: automorphic (V. sepium L.), transitoric (V. angustifolia L., V. sativa L., V. villosa Roth, V. cracca L.) and flat, epimorphic (V. hirsuta (L.) S. F.
Małgorzata Stpiczyńska, Jacek Pielecki
doaj   +1 more source

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