Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Activation volumes associated with excited-state electron transfer across amidinium-carboxylate bridge. [PDF]
Langford D +8 more
europepmc +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Assessing the Potential for Agroforestry in Pokhara, Nepal: An Investigation of the Decline of Agricultural Land Use Along a Rural-Urban Gradient and Land Suitability Analysis. [PDF]
Subedi R +4 more
europepmc +1 more source
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
SARS-CoV-2 crossreactive B-cells outnumber seasonal coronavirus spike-specific clones at the end of the COVID-19 pandemic. [PDF]
Gonzalez-Lopez C +13 more
europepmc +1 more source
Insights into tautomerism and pH effects on the photoluminescence of citric acid-derived molecular fluorophores. [PDF]
Estévez L, Otero N.
europepmc +1 more source
Draft genome sequence of potential probiotic <i>Lacticaseibacillus paracasei</i> subsp. <i>paracasei</i> S1 isolated from <i>Nypa fruticans</i> Wurmb. in Cagayan, Northern Philippines. [PDF]
Balloyan LR +5 more
europepmc +1 more source
Slow Thinking for Fast Results: Reclaiming Analytical Reasoning in Antimicrobial Susceptibility Test Interpretation. [PDF]
Kiffer CRV, Bispo PJM.
europepmc +1 more source
Hydrogen bonds or not? Synthesis and structure of 2,3-di-cyanona-phthalene-1,4-diyl bis-(4-methylbenzene-1-sulfonate). [PDF]
Akdemir N, Tahir MN, Ashfaq M.
europepmc +1 more source

