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First records of Tropidurus madeiramamore Carvalho, Paredero, Villalobos-Chaves, Ferreira, Rodrigues & Curcio, 2024 (Squamata, Tropiduridae) from Bolivia [PDF]

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This note reports the first country records of Tropidurus madeiramamore Carvalho, Paredero, Villalobos-Chaves, Ferreira, Rodrigues & Curcio, 2024 for Bolivia, all northern Beni Department, extending the range by some 300 km to the west of earlier
Robert P. Langstroth, Mauricio Herrera, Gabriel Callapa, Luis R. Rivas, Lucindo Gonzales, Lesly López, Anthony R. DiMeglio, Gregory Schneider, Robert B. Wallace   +8 more
doaj   +3 more sources

Fully automated sequential immunofluorescence (seqIF) for hyperplex spatial proteomics

Scientific Reports, 2023
Tissues are complex environments where different cell types are in constant interaction with each other and with non-cellular components. Preserving the spatial context during proteomics analyses of tissue samples has become an important objective for ...
François Rivest, Deniz Eroglu, Benjamin Pelz, Joanna Kowal, Alexandre Kehren, Vytautas Navikas, Maria Giuseppina Procopio, Pino Bordignon, Emilie Pérès, Marco Ammann, Emmanuel Dorel, Sylvain Scalmazzi, Lorenzo Bruno, Matthieu Ruegg, Gabriel Campargue, Gilles Casqueiro, Lionel Arn, Jérôme Fischer, Saska Brajkovic, Pierre Joris, Marco Cassano, Diego Dupouy   +21 more
doaj   +1 more source

Substantial Assistance and Sentence Severity: Is There a Correlation Substantial Assistance [PDF]

, 1998
How much more severe are sentences imposed in districts with low substantial assistance rates than those in which the rate is very high? In the aggregate, not at all. At first blush this may puzzle readers because substantial assistance (SA) departures
Weinstein, Ian
core   +2 more sources

Modeling the disruption of respiratory disease clinical trials by non-pharmaceutical COVID-19 interventions

Nature Communications, 2022
A computational mechanistic viral infection model and trial simulation advocates for adaptation of respiratory disease clinical trials whose chances of success and interpretability are being degraded under COVID-19 pandemic mitigation measures.
Simon Arsène, Claire Couty, Igor Faddeenkov, Natacha Go, Solène Granjeon-Noriot, Daniel Šmít, Riad Kahoul, Ben Illigens, Jean-Pierre Boissel, Aude Chevalier, Lorenz Lehr, Christian Pasquali, Alexander Kulesza   +12 more
doaj   +1 more source

Endophyte-Mediated Resistance in Tomato to Fusarium oxysporum Is Independent of ET, JA, and SA

Frontiers in Plant Science, 2019
Root endophytes can confer resistance against plant pathogens by direct antagonism or via the host by triggering induced resistance. The latter response typically relies on jasmonic acid (JA)/ethylene (ET)-depended signaling pathways, but can also be ...
M. Constantin, Francisco J. de Lamo, Babette V. Vlieger, M. Rep, F. Takken   +4 more
semanticscholar   +1 more source

A computational 2D model simulating the neural responses of a single tactile unit to vibrotactile stimuli

Journal of Biomechanical Science and Engineering
This study presents a computational model that simulates the responses of tactile afferents, which are essential for designing tactile devices in addition to understanding the mechanism of tactile perception of vibrotactile stimuli.
Hiroki ISHIZUKA, Shoki KITAGUCHI, Masashi NAKATANI, Hidenori YOSHIMURA, Fusao SHIMOKAWA   +4 more
doaj   +1 more source

MT@SiO2 Enhances MEK5‐MAPK6‐NAC32 Mediated Salicylic Acid Synthesis Which Increases Resistance to Glomerella Leaf Spot in Apple

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2318-2334, April 2026.
ABSTRACT Glomerella leaf spot (GLS), a fungal disease caused by Colletotrichum fructicola, is a major destructive disease of apples but research on control measures is limited. Melatonin (MT) is a phytohormone‐like compound that affects plant growth and stress response but is prone to light‐induced degradation, resulting in low stability and efficacy ...
Yong Zhang, Guangming Ma, Lijie Gao, Xian Pu, Moxian Chen, Xiaodong Zheng, Michael Wisniewski, Xiangyang Li   +7 more
wiley   +1 more source

No General Association Between Myositis Antibodies and Electromyography Findings

Neurology and Clinical Neuroscience, Volume 14, Issue 2, Page 160-167, March 2026.
ABSTRACT Objective Myositis‐specific antibodies (MSAs), myositis‐associated antibodies (MAAs), and concentric needle electromyography (EMG) are routinely used in the differential diagnosis of myositis. Their mutual relationship, particularly between MSAs/MAAs and EMG findings, remains unclear.
Benedict Kleiser, Hanna Seifermann, David Hoffmann, Markus C. Kowarik, Evelyn Dubois, Marcel Armbruster, Alexander Grimm, Justus Marquetand   +7 more
wiley   +1 more source

SA-49, a novel aloperine derivative, induces MITF-dependent lysosomal degradation of PD-L1

EBioMedicine, 2019
Background Programmed death-ligand 1 (PD-L1) is a T-cell inhibitory checkpoint molecule that suppresses antitumor immunity. Anti-PD-L1 antibodies have shown remarkable promise in treating tumors, but the patient response rate is low.
N. Zhang, Yueying Dou, Lu Liu, Xin Zhang, Xiaojiao Liu, Qingxuan Zeng, Yang Liu, M. Yin, Xiuju Liu, Hongbin Deng, Danqing Song   +10 more
semanticscholar   +1 more source

Quantification of Propargylated RNA Nucleosides After Metabolic Labeling Via the Methylation Pathway

ChemBioChem, Volume 26, Issue 7, April 1, 2025.
Methylation is the most prevalent RNA modification, facilitated by S‐adenosyl‐L‐methionine (SAM) and various methyltransferases (MTases). This work uses a clickable SAM analog to investigate nucleoside modifications in HEK293T cells by mass spectrometric analysis after metabolic labeling with propargylselenohomocysteine (PSH).
Nadine A. Kueck, Sabine Hüwel, Arne Hoffmann, Andrea Rentmeister   +3 more
wiley   +1 more source