Results 121 to 130 of about 43,901 (304)

Diacerein Disrupts Testicular Homeostasis: The Essential Role of Basal Cytokines in Maintaining Sertoli Cell Integrity and the Immune Microenvironment

open access: yesAndrology, EarlyView.
ABSTRACT Background Pro‐inflammatory cytokines, TNF and IL‐1B, are essential for testicular homeostasis. Diacerein, an anti‐inflammatory drug, inhibits these cytokines, impairing M2 macrophages and Leydig cells (LCs). However, its impact on Sertoli cells (SCs) and M1 (CD68) macrophages remains unknown.
Elide Loise Freitas de Jesus   +6 more
wiley   +1 more source

Addressing the Challenges of Translating LRRK2 Biology into Disease‐Modifying Therapies: The LRRK2 Investigative Therapeutics Exchange Initiative

open access: yes
Movement Disorders, EarlyView.
Esther Sammler   +12 more
wiley   +1 more source

Impact of incretin analogues on lipid and lipoprotein metabolism in obesity and diabetes

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Incretin‐based therapies have gained momentum as a key strategy for reducing cardiovascular risk in individuals with obesity and/or type 2 diabetes (T2D). It remains unclear whether the cardiovascular benefits reflect a direct reduction in atherogenic lipoproteins—namely, low‐density lipoproteins (LDL), very low‐density lipoproteins (VLDL) and
Andrea Baragetti, Giuseppe Danilo Norata
wiley   +1 more source

Attention Based Optimization for 3D Shape Registration

open access: yesComputer Graphics Forum, EarlyView.
Abstract Transformers are sequence‐to‐sequence architectures originally designed to handle structurally rigid and order‐sensitive data, such as text and images. At their core, they exploit the attention mechanism, which is permutation‐equivariant and relies on computing token‐to‐token relationships.
A. Riva, L. Olearo, S. Melzi
wiley   +1 more source

Interformat equivalence between paper and electronic administrations of the self-assessment anhedonia scale in a substance use disorder clinical sample. [PDF]

open access: yesFront Psychol
Sanjuán Y   +12 more
europepmc   +1 more source

MotionPyramid: Controllable Motion Synthesis via Stylized Phase Manifolds

open access: yesComputer Graphics Forum, EarlyView.
Abstract We introduce stylized phase manifolds—a compact, interpretable latent representation that disentangles motion content (e.g. “jumping”, “walking”), the temporal structure (e.g. motion cycle frequency, gait timing), and style (i.e. how the motion is performed). Learned in an unsupervised manner and inherently low‐dimensional, the manifold offers
Jingyuan Li   +3 more
wiley   +1 more source

Serological and biochemical characterization of Aspergillus fumigatus Asp f 10 as a potential diagnostic marker in ABPA and related respiratory diseases. [PDF]

open access: yesFront Allergy
Ghosh S   +7 more
europepmc   +1 more source

Пракса површног читања

open access: yesКњижевна историја
Nemanja Mitrović
doaj   +1 more source

Factors Associated With Progression From Level 1 to Level 2 Sensor‐Detected Hypoglycaemia in People With Type 1 and Insulin‐Treated Type 2 Diabetes: A Post Hoc Analysis From the Hypo‐METRICS Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims We investigated the proportion of sensor‐detected hypoglycaemic (SDH) events progressing to level 2, and associated variables. Materials and Methods We used data from Hypo‐METRICS, which recruited people with type 1 (pwT1D) and insulin‐treated type 2 diabetes (pwT2D) with ≥ 1 hypoglycaemic event in preceding 3 months, wearing blinded ...
Vaios Koutroukas   +15 more
wiley   +1 more source

SAA [PDF]

open access: yes, 2019
openaire   +1 more source

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