Results 111 to 120 of about 61,216 (332)
Clinical Pharmacology in Drug Development, EarlyView.Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan +7 more
wiley +1 more source
How Laminar Frontal Cortex and Basal Ganglia Circuits Interact to Control Planned and Reactive Saccades [PDF]
, 2000 The basal ganglia and frontal cortex together allow animals to learn adaptive responses that acquire rewards when prepotent reflexive responses are insufficient.
Brown, Joshua +2 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Cannabidiol (CBD) is approved as an adjunctive treatment of seizures associated with Dravet syndrome, Lennox–Gastaut Syndrome, and tuberous sclerosis. Its therapeutic and adverse effects are thought to arise, at least partly, from a pharmacokinetic interaction with clobazam, another anti‐seizure medication (ASM).
Andriy A. Gorbenko +7 more
wiley +1 more source
How Listing's Law May Emerge from Neural Control of Reactive Saccades [PDF]
, 1995 We hypothesize that Listing's Law emerges as a result of two key properties of the saccadic sensory-motor system: 1) The visual sensory apparatus has a 2-D topology and 2) motor synergists are synchronized.
Bullock, Daniel, Pribe, Christopher A.
core +1 more source
Pro-saccades and anti-saccades to onset and offset targets
Vision Research, 2005 Pro- and anti-saccades made to either onset or offset targets were examined to determine which of (1) changes in luminance or (2) the appearance of new peripheral objects, is more important in the reflexive generation of pro-saccades. In two experiments, pro-saccades had faster reaction times than did anti-saccades, but the difference was much greater ...
Jay Pratt, Leo Trottier
openaire +2 more sources
Itinerant curriculum theory: People's theory against the field's epistemicidal ethos
The Curriculum Journal, EarlyView.Abstract The field of curriculum studies suffers from a glaring theoretical impasse. Much of this impasse has been rightly attributed to the triumphalism of the neoliberal wave that has massacred the educational hemisphere with policies and practices that reduce pedagogy to an instrumentalist praxis directly associated with the thirsty desires and ...
João M. Paraskeva
wiley +1 more source
Saccadic Behavior during the Response to Pure Vergence Stimuli I: General Properties
Journal of Eye Movement Research, 2007 If two targets are carefully aligned so that they fall along the cyclopean axis, the required eye movement will be symmetrical with the two eyes turning equally inward or outward. When such “pure vergence stimuli” are used only a “pure vergence movement”
John Semmlow +3 more
doaj +1 more source
Epileptic Disorders, EarlyView.Abstract Although inborn errors of metabolism (IEM) are a rare cause of epilepsy, seizures are a common presentation in these disorders. Seizures in IEM are frequently refractory to conventional anti‐seizure medication and might warrant initiation of specific treatments based on vitamins or dietary modifications or provision of alternative substrates ...
D. Kapoor +7 more
wiley +1 more source
Epileptic Disorders, EarlyView.Abstract The accurate interpretation of scalp EEG remains an instrumental diagnostic component of epilepsy care. Knowledge of what constitutes normal EEG findings, non‐epileptiform abnormalities, and epileptiform patterns—both ictal and interictal—is essential for appropriate patient management.
Juan Luis Alcala‐Zermeno +9 more
wiley +1 more source
The relation of the phase-locked fixation saccade-linked component of alpha rhythm to change of stimulus illuminance [PDF]
, 1966 Kenneth Gaarder +2 more
openalex +1 more source