Results 211 to 220 of about 37,346 (289)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux   +26 more
wiley   +1 more source

Early Visual Development in Albinism

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Visual system development is incomplete at birth, and while fixation and tracking usually emerge within the first weeks of life, some infants show delayed visual development (DVDev). This is frequently observed in infants with albinism, yet the timing of visual attentiveness and subsequent visual acuity development remains unclear ...
Catelijne Maria Neijzen   +6 more
wiley   +1 more source

‘Talk to Us, Not About Us’: Children's Understandings and Experiences of Participation in Australian Family Law

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT A hive of recent policy and legislative activity in Australian family law has emphasized the importance of children's right to participate in decision‐making following parental separation. Yet a powerful tension persists between supporting children's right to participation and protecting children from parental conflict.
Georgina Dimopoulos   +3 more
wiley   +1 more source

A New Case of Lethal Congenital Contracture Syndrome Type 3 With Hyperinsulinism and Optic Atrophy

open access: yesClinical Genetics, EarlyView.
PIP5K1C‐related lethal congenital contracture syndrome with hyperinsulinism and optic atrophy. ABSTRACT Lethal congenital contracture syndrome 3 (LCCS3, MIM #611369) is a rare autosomal recessive neuromuscular disorder caused by biallelic loss‐of‐function (LOF) variants in PIP5K1C, reported in only two families to date.
Tameemi Abdalla Moady   +3 more
wiley   +1 more source

Age-related changes in saccade behavior. [PDF]

open access: yesSci Rep
Boz HE   +5 more
europepmc   +1 more source

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