Results 261 to 270 of about 59,407 (333)

Deep brain stimulation of the centromedian nucleus for drug‐resistant epilepsy in children: Quality‐of‐life and functional outcomes from the CHILD‐DBS registry

Epilepsia, EarlyView.
Abstract Objective Deep brain stimulation of the centromedian nucleus of the thalamus (CM‐DBS) is an investigational, off‐label treatment for drug‐resistant epilepsy (DRE) in children. Although emerging evidence supports its safety and efficacy for select indications, the effect of CM‐DBS on quality of life and functional outcomes such as school ...
Karim Mithani, Farbod Niazi, Hrishikesh Suresh, Yousof Alrumayyan, Eriberto R. Rayco, Ayako Ochi, Hiroshi Otsubo, Elizabeth Kerr, Sara Breitbart, Andrea LeBlanc‐Millar, Nisha Gadgil, Jeffrey S. Raskin, Alexander G. Weil, Aristides Hadjinicolaou, Christian Iorio‐Morin, Shelly Weiss, Puneet Jain, Lauren Sham, Elizabeth Donner, Alfonso Fasano, Carolina Gorodetsky, George M. Ibrahim   +21 more
wiley   +1 more source

Otoneurological evaluation: definitions and scientific evidence of bedside assessment and complementary exams. Outcomes of the II Brazilian Forum of Otoneurology. [PDF]

Braz J Otorhinolaryngol
Salmito MC, Morganti LOG, Venosa AR, Ganança FF, Ganança MM, Mezzalira R, Bittar RSM, Ramos BF, Dias CM, Real DM, Gonçalves DU, Zuma E Maia FC, Lopes KC, Santos MAO, Machado PLF, Albertino RS, Cal RVR, Dorigueto RS, Silva RC, Carvalho RCB, Albertino S.   +20 more
europepmc   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

Eye movements and user emotional experience: a study in interface design. [PDF]

Front Psychol
Sun N, Jiang Y.
europepmc   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications. 1. Use of the EEG in drug development and characteristics of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof‐of‐principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalography (EEG) response (PPR) as a surrogate for seizures, is currently the only human model that allows POP trials of investigational compounds after ...
Dorothée Kasteleijn‐Nolst Trenité, Wolfgang Löscher   +1 more
wiley   +1 more source

Joint examination of reflexive vertical saccades and small involuntary fixational saccades improves the classification of patients with progressive supranuclear palsy (PSP): a ROC study. [PDF]

Exp Brain Res
Becker W, Vintonyak O, Kassubek J.
europepmc   +1 more source

Familial SYNGAP1 variants define the boundaries of a complex neurodevelopmental disorder with epilepsy

Epilepsia, EarlyView.
Abstract Objective SYNGAP1‐related disorders are common neurodevelopmental conditions characterized by autism spectrum disorder, developmental delay, intellectual disability, and a range of generalized seizure types. Disease‐causing variants in SYNGAP1 typically occur de novo. This study aims to characterize inherited cases of SYNGAP1‐related disorders.
Alicia G. Harrison, Jan H. Magielski, Ian McSalley, Shiva Ganesan, Anna J. Prentice, Kristin G. Cunningham, Samuel R. Pierce, Michael J. Boland, Benjamin L. Prosser, Ingo Helbig, Jillian L. McKee   +10 more
wiley   +1 more source

Identifying depression with mixed features: the potential value of eye-tracking features. [PDF]

Front Neurol
Liu XC, Chen M, Ji YJ, Chen HB, Lin YQ, Xiao Z, Guan QY, Ou WQ, Wang YY, Xiao QL, Huang XC, Zhang JF, Huang YK, Yu QT, Jiang MJ.   +14 more
europepmc   +1 more source

High-fidelity but hypometric spatial localization of afterimages across saccades

Schweitzer R, Seel T, Raisch J, Rolfs M.
europepmc   +1 more source

The visual system does not operate like a camera. [PDF]

J Vis
Rucci M, Ahissar E, Burr DC, Kagan I, Poletti M, Victor JD.   +5 more
europepmc   +1 more source