Results 41 to 50 of about 1,785,581 (311)
Integral Membrane Protein Expression in Saccharomyces cerevisiae [PDF]
Eukaryotic integral membrane proteins are challenging targets for crystallography or functional characterization in a purified state. Since expression is often a limiting factor when studying this difficult class of biological macromolecules, the intent of this chapter is to focus on the expression of eukaryotic integral membrane proteins (IMPs) using ...
Boswell-Casteel, Rebba C +3 more
openaire +4 more sources
Identification of novel human damage response proteins targeted through yeast orthology. [PDF]
Studies in Saccharomyces cerevisiae show that many proteins influence cellular survival upon exposure to DNA damaging agents. We hypothesized that human orthologs of these S.
J Peter Svensson +4 more
doaj +1 more source
Control of yeast retrotransposons mediated through nucleoporin evolution. [PDF]
Yeasts serve as hosts to several types of genetic parasites. Few studies have addressed the evolutionary trajectory of yeast genes that control the stable co-existence of these parasites with their host cell.
Paul A Rowley +3 more
doaj +1 more source
Life requires the oligomerization of individual proteins into higher-order assemblies. In order to form functional oligomers, monomers must adopt appropriate 3D structures.
Ashley S Denney +2 more
doaj +1 more source
The zinc cluster protein Sut1 contributes to filamentation in Saccharomyces cerevisiae [PDF]
Copyright © 2013, American Society for Microbiology. All Rights ReservedSut1 is a transcriptional regulator of the Zn(II)(2)Cys(6) family in the budding yeast Saccharomyces cerevisiae.
Höfken, T +5 more
core +1 more source
Saccharomyces cerevisiae is one of the most extensively used biosynthetic systems for the production of diverse bioproducts, especially biotherapeutics and recombinant proteins. Because the expression and insertion of foreign genes are always impaired by
Yijian Wu +5 more
doaj +1 more source
Evolutionary genomics of transposable elements in Saccharomyces cerevisiae [PDF]
Saccharomyces cerevisiae is one of the premier model systems for studying the genomics and evolution of transposable elements. The availability of the S.
Bensasson, Douda +8 more
core +1 more source
Kcc4 associates with septin proteins of Saccharomyces cerevisiae [PDF]
Kcc4, a kinase of the budding yeast Saccharomyces cerevisiae, is homologous to the bud neck protein kinases Hsl1/Nik1 and Gin4. We report here that a GFP‐Kcc4 fusion protein is localized at the bud neck and that the non‐kinase domain is required for this localization. We also demonstrate that Kcc4 associates with septin proteins in vitro and in vivo by
Okuzaki, Daisuke, Nojima, Hiroshi
openaire +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Global analysis of protein homomerization in Saccharomyces cerevisiae [PDF]
In vivo analyses of the occurrence, subcellular localization, and dynamics of protein–protein interactions (PPIs) are important issues in functional proteomic studies. The bimolecular fluorescence complementation (BiFC) assay has many advantages in that it provides a reliable way to detect PPIs in living cells with minimal perturbation of the structure
Kim, Yeonsoo +3 more
openaire +2 more sources

