Results 41 to 50 of about 155,571 (316)

Control of yeast retrotransposons mediated through nucleoporin evolution. [PDF]

PLoS Genetics, 2018
Yeasts serve as hosts to several types of genetic parasites. Few studies have addressed the evolutionary trajectory of yeast genes that control the stable co-existence of these parasites with their host cell.
Paul A Rowley, Kurt Patterson, Suzanne B Sandmeyer, Sara L Sawyer   +3 more
doaj   +1 more source

The yeast vacuolar membrane proteome [PDF]

, 2009
Transport of solutes between the cytosol and the vacuolar lumen is of crucial importance for various functions of vacuoles, including ion homeostasis; detoxification; storage of different molecules such as amino acids, phosphate, and calcium ions; and ...
Poolman, Bert,, Slotboom, Dirk J.,, Breitling, Rainer, Permentier, Hjalmar P.,, Gandhi, Tejas, Breitling, R., Breitling, Rainer,, Slotboom, D.J., Gandhi, Tejas,, Permentier, Hjalmar P., Permentier, H.P., Gandhi, T., Wiederhold, Elena,, Poolman, Bert, Wiederhold, Elena, Wiederhold, E., Poolman, B., Permentier, Hjalmar P.; id_orcid, Slotboom, Dirk J.   +18 more
core   +1 more source

Kcc4 associates with septin proteins of Saccharomyces cerevisiae [PDF]

FEBS Letters, 2001
Kcc4, a kinase of the budding yeast Saccharomyces cerevisiae, is homologous to the bud neck protein kinases Hsl1/Nik1 and Gin4. We report here that a GFP‐Kcc4 fusion protein is localized at the bud neck and that the non‐kinase domain is required for this localization. We also demonstrate that Kcc4 associates with septin proteins in vitro and in vivo by
Okuzaki, Daisuke, Nojima, Hiroshi
openaire   +2 more sources

An outlook to sophisticated technologies and novel developments for metabolic regulation in the Saccharomyces cerevisiae expression system

Frontiers in Bioengineering and Biotechnology, 2023
Saccharomyces cerevisiae is one of the most extensively used biosynthetic systems for the production of diverse bioproducts, especially biotherapeutics and recombinant proteins. Because the expression and insertion of foreign genes are always impaired by
Yijian Wu, Sai Feng, Zeao Sun, Yan Hu, Xiao Jia, Bin Zeng   +5 more
doaj   +1 more source

Global analysis of protein homomerization in Saccharomyces cerevisiae [PDF]

Genome Research, 2018
In vivo analyses of the occurrence, subcellular localization, and dynamics of protein–protein interactions (PPIs) are important issues in functional proteomic studies. The bimolecular fluorescence complementation (BiFC) assay has many advantages in that it provides a reliable way to detect PPIs in living cells with minimal perturbation of the structure
Kim, Yeonsoo, Jung, Jong Pil, Pack, Chan-Gi, Huh, Won-Ki   +3 more
openaire   +2 more sources

Thermoconditional modulation of the pleiotropic sensitivity phenotype by the Saccharomyces cerevisiae PRP19 mutant allele pso4-1

, 2002
The conditionally-lethal pso4-1 mutant allele of the spliceosomal-associated PRP19 gene allowed us to study this gene’s influence on pre-mRNA processing, DNA repair and sporulation.
Brendel, Martin (Prof. Dr.), Grey, Martin, Revers, L. F, Bonatto, Diego, Saffi, Jenifer, Feldmann, H., Henriques, Joao A. P., Cardone, Jacqueline Moraes   +7 more
core   +1 more source

Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae [PDF]

Genetics, 2016
Abstract In this review, we provide an overview of protein synthesis in the yeast Saccharomyces cerevisiae. The mechanism of protein synthesis is well conserved between yeast and other eukaryotes, and molecular genetic studies in budding yeast have provided critical insights into the fundamental process of translation as well as its ...
Dever, Thomas E., Kinzy, Terri Goss, Pavitt, Graham D   +2 more
openaire   +3 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Growth-rate regulated genes have profound impact on interpretation of transcriptome profiling in Saccharomyces cerevisiae [PDF]

, 2006
Background: Growth rate is central to the development of cells in all organisms. However, little is known about the impact of changing growth rates. We used continuous cultures to control growth rate and studied the transcriptional program of the model ...
Nielsen, Jens, Åkesson, Mats, Regenberg, Birgitte, Winther, Ole, Grotkjaer, Thomas, Grotkjær, Thomas, Fausbøll, Anders, Bro, Christoffer, Hansen, Lars Kai, Brunak, Søren, Ole, Winther   +10 more
core   +1 more source

Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

G3: Genes, Genomes, Genetics, 2016
The TTT complex is composed of the three essential proteins Tel2, Tti1, and Tti2. The complex is required to maintain steady state levels of phosphatidylinositol 3-kinase-related kinase (PIKK) proteins, including mTOR, ATM/Tel1, ATR/Mec1, and TRRAP/Tra1,
Kyle S. Hoffman, Martin L. Duennwald, Jim Karagiannis, Julie Genereaux, Alexander S. McCarton, Christopher J. Brandl   +5 more
doaj   +1 more source