Results 181 to 190 of about 339,186 (289)

Phytohormonal and Transcriptomic Mechanisms of Multigenerational Stress Memory in Wheat Under Weed Competition

open access: yesPlant, Cell &Environment, Volume 49, Issue 6, Page 3436-3454, June 2026.
ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng   +4 more
wiley   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, Volume 20, Issue 5, Page 1299-1322, May 2026.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Yield, stability, and plasticity of Arabica coffee genotypes under contrasting pruning systems

open access: yesAgronomy Journal, Volume 118, Issue 3, May/June 2026.
Abstract Coffee yield instability caused by biennial bearing causes coffee yield instability, reducing production predictability and farm income. Biennial drastic pruning (Zero Crop), which alternates harvest and no‐harvest years, has been proposed to reduce this instability, but its benefits depend on genotype performance under contrasting management.
Weverton Pereira Rodrigues   +5 more
wiley   +1 more source

Pre‐analytical guidelines for blood and CSF Biomarkers 2025: Recommendations from the NACC ADRC Biofluid Biomarker Best Practices Workgroup

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract The Biofluid Biomarkers Best Practices Workgroup of the National Alzheimer's Coordinating Center–Alzheimer's Disease Research Center (ADRC) Biomarker Core Steering Committee was convened to update pre‐analytical handling guidelines for biofluid biomarkers, focusing on cerebrospinal fluid (CSF) and blood.
Timothy E. Van Meter   +21 more
wiley   +1 more source

Association between proximity to a lead‐releasing facility and cognition in diverse cohorts

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract BACKGROUND The associations between adult lead exposure and late‐life cognition are largely unknown. METHODS In two cohorts, Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE, n = 1638) and Study of Healthy Aging in African Americans (STAR, n = 741), we assessed residential proximity to lead‐releasing facilities for association with ...
Scarlet Cockell   +9 more
wiley   +1 more source

Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract BACKGROUND Genetic variants affecting microglial function can influence Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. The AD‐associated ABI3S209F (Abi3S212F in mouse) variant regulates cytoskeletal dynamics, but its in vivo impact on pathology is unknown. METHODS: An Abi3S212F mouse was developed and crossed with
Claire A. Butler   +29 more
wiley   +1 more source

Effects of α‐synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION α‐Synuclein is the hallmark pathology of Parkinson's disease and dementia with Lewy bodies, described together as Lewy body disease (LBD). We investigated effects of α‐syn biomarker positivity in clinically unimpaired (CU) individuals.
Joseph R. Winer   +22 more
wiley   +1 more source

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