ABSTRACT Multigenerational stress exposure induces stress memory in plants, influencing resource allocation, defence mechanisms, and productivity. Weed competition imposes both resource‐based (abiotic) and allelopathic (biotic) stress, engaging overlapping hormonal pathways.
Albert O. Kwarteng +4 more
wiley +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Health and Social Justice in the 21st Century. [PDF]
Furio FK.
europepmc +1 more source
Trends in Reconstructive Hip Surgery for Cerebral Palsy in U.S. Community Hospitals Before and After Publication of National Hip Surveillance Guidelines. [PDF]
Kong S +4 more
europepmc +1 more source
Yield, stability, and plasticity of Arabica coffee genotypes under contrasting pruning systems
Abstract Coffee yield instability caused by biennial bearing causes coffee yield instability, reducing production predictability and farm income. Biennial drastic pruning (Zero Crop), which alternates harvest and no‐harvest years, has been proposed to reduce this instability, but its benefits depend on genotype performance under contrasting management.
Weverton Pereira Rodrigues +5 more
wiley +1 more source
Abstract The Biofluid Biomarkers Best Practices Workgroup of the National Alzheimer's Coordinating Center–Alzheimer's Disease Research Center (ADRC) Biomarker Core Steering Committee was convened to update pre‐analytical handling guidelines for biofluid biomarkers, focusing on cerebrospinal fluid (CSF) and blood.
Timothy E. Van Meter +21 more
wiley +1 more source
Fully Covered Self-Expandable Metal Stent Placement for Management of a Perforated Duodenal Ulcer With Persistent Leak in a Decompensated Cirrhotic. [PDF]
Vu J, Pecha RL, Yen AW, Rachakonda V.
europepmc +1 more source
Association between proximity to a lead‐releasing facility and cognition in diverse cohorts
Abstract BACKGROUND The associations between adult lead exposure and late‐life cognition are largely unknown. METHODS In two cohorts, Kaiser Healthy Aging and Diverse Life Experiences (KHANDLE, n = 1638) and Study of Healthy Aging in African Americans (STAR, n = 741), we assessed residential proximity to lead‐releasing facilities for association with ...
Scarlet Cockell +9 more
wiley +1 more source
Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia
Abstract BACKGROUND Genetic variants affecting microglial function can influence Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. The AD‐associated ABI3S209F (Abi3S212F in mouse) variant regulates cytoskeletal dynamics, but its in vivo impact on pathology is unknown. METHODS: An Abi3S212F mouse was developed and crossed with
Claire A. Butler +29 more
wiley +1 more source
Effects of α‐synuclein pathology on synaptic dysfunction and clinical outcomes in normal aging
Abstract INTRODUCTION α‐Synuclein is the hallmark pathology of Parkinson's disease and dementia with Lewy bodies, described together as Lewy body disease (LBD). We investigated effects of α‐syn biomarker positivity in clinically unimpaired (CU) individuals.
Joseph R. Winer +22 more
wiley +1 more source

