Results 161 to 170 of about 1,961 (261)

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor   +5 more
wiley   +1 more source

Teología Dogmática. I: Introducción a la Teología, Cristología, La Trinidad, Pneumatología, Mariología; II: Creación, Antropología, Eclesiología, Sacramentos, Escatología [RESEÑA]

open access: yes, 2013
Aurelio FERNÁNDEZ, Teología Dogmática. I: Introducción a la Teología, Cristología, La Trinidad, Pneumatología, Mariología; II: Creación, Antropología, Eclesiología, Sacramentos, Escatología, Madrid: BAC, 2012, 640 y 800 ...
Izquierdo, C. (Cesar)
core  

Exercise training prior to and during cancer in mice preserves muscle mass, reduces tumour weight and suppresses molecular mediators of cachexia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend PoWeR training (11.5 weeks of voluntary wheel running with progressively increased resistance) before and during cancer attenuates muscle loss, limits tumour growth, drives a transition toward a more oxidative muscle phenotype (IIB‐to‐IIA shift), downregulates cachexia‐associated pathways and enhances mitochondrial performance in
Stavroula Tsitkanou   +13 more
wiley   +1 more source

Sensitive Period Analysis of Adulthood BMI and Cancer Risk: An Individual Participant Data Meta‐Analysis of Over 720,000 Participants in the ABACus 2 Consortium

open access: yesInternational Journal of Cancer, Volume 159, Issue 4, Page 960-972, 15 August 2026.
Over a dozen cancers have been associated with excess body mass index, primarily in mid‐to‐late adulthood. Whether obesity‐related cancer risk differs across adulthood remains unclear. Using the Sensitive Periods Model and super‐landmarking approaches, this study found that higher BMI increased obesity‐related cancer risk across ages 30–65.
Nadin K. Hawwash   +13 more
wiley   +1 more source

Patient‐reported outcomes in castration‐resistant prostate cancer with bone metastases treated with radium‐223 with or without olaparib

open access: yesCancer, Volume 132, Issue 13, 1 July 2026.
Abstract Background The combination of olaparib plus radium‐223 improved progression‐free survival in patients with metastatic castration‐resistant prostate cancer with bone metastases (BM) in the multicenter, randomized, phase 2 COMRADE trial (NCT03317391). Here, the patient‐reported outcome (PRO) analysis of this trial is reported.
Rana R. McKay   +11 more
wiley   +1 more source

Selection of standards for estimated fetal weight percentiles

open access: yesPregnancy, Volume 2, Issue 4, July 2026.
Abstract Objectives To evaluate which of 10 standards or references should be used for determination of percentiles of estimated fetal weight (EFW). Study design Cross‐sectional study using pooled data from four maternal‐fetal medicine (MFM) practices. Inclusion criteria were as follows: ultrasound exam during 2022, singleton fetus, gestational age 240/
C. Andrew Combs   +4 more
wiley   +1 more source

Praxis administrativa: curia diocesana y parroquia, disciplina sacramentos, función enseñar. Programa docente curso 2024/2025

open access: yes
Programa docente de la asignatura Praxis administrativa: curia diocesana y parroquia, disciplina sacramentos, función enseñar para el curso 2024/2025 impartida por el profesor Domingo Moreno ...
Moreno Ramírez, Domingo
core  

Red‐Pi: A Low‐Cost Red Teaming Platform for Water Infrastructure Security Assessment

open access: yesSECURITY AND PRIVACY, Volume 9, Issue 4, July/August 2026.
ABSTRACT The water and wastewater sector faces growing cyber threats due to rapid digitalization and the use of IoT‐based control systems. Many utilities manage essential services that affect public health and the environment but do not have enough cybersecurity staff and cannot afford regular security tests.
Agustin Di Bartolo   +5 more
wiley   +1 more source

Oxidative Stress Induced Senescent Macrophage‐Driven Squamous Cell Carcinoma Invasion via Glutamine Metabolic Reprogramming

open access: yesAging Cell, Volume 25, Issue 7, July 2026.
Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang   +7 more
wiley   +1 more source

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