Results 31 to 40 of about 4,107 (168)

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Pelvic venous disorders in women: Diagnosis and management for gynecologists

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pelvic venous disorders (PeVD) are an underrecognized yet significant cause of chronic pelvic pain (CPP) in reproductive‐aged women, characterized by venous reflux, obstruction, or both. This clinical opinion provides a practical overview of PeVD for gynecologists, outlining its pathophysiology, common presentations, diagnostic approach, and ...
Tiffany Ni, Inbar Friedman, Jessica Smith, Brian Liu, Mary Melchior, Andrew D. Brown   +5 more
wiley   +1 more source

Patient-Specific 3D Virtual Surgical Planning Using Simulated Fluoroscopic Images to Improve Sacroiliac Joint Fusion

Biomechanics, 2023
Sacroiliac (SI) joint dysfunction can lead to debilitating pain but can be treated with minimally invasive sacroiliac joint fusion (SIJF). This treatment is commonly performed using 2D fluoroscopic guidance.
Nick Kampkuiper, Jorm Nellensteijn, Edsko Hekman, Gabriëlle Tuijthof, Steven Lankheet, Maaike Koenrades, Femke Schröder   +6 more
doaj   +1 more source

Analysis of balance in adults with chronic axial spinal pain receiving medial branch block or radiofrequency ablation procedures

PM&R, EarlyView.
Abstract Background Medial branch blocks (MBB) and radiofrequency ablations (RFA) are common diagnostic, prognostic, and interventional procedures performed for the management of cervical and lumbar spine facetogenic pain. Although these procedures have established utility as pain management strategies, it is unclear if the disruption in function of ...
Matthew Carter, John D Ralston, Robert Burnham, Jennifer Laxshimalla, Lisa Jasper, JuliAnn Thai, Ashley D Smith   +6 more
wiley   +1 more source

A Review and Algorithm in the Diagnosis and Treatment of Sacroiliac Joint Pain

Journal of Pain Research, 2020
Steven Falowski,1 Dawood Sayed,2 Jason Pope,3 Denis Patterson,4 Michael Fishman,5 Mayank Gupta,6 Pankaj Mehta7 1Neurosurgical Associates of Lancaster, Lancaster, PA 17601, USA; 2University of Kansas, Kansas City, KS, USA; 3Evolve Restorative Center ...
Falowski S, Sayed D, Pope J, Patterson D, Fishman M, Gupta M, Mehta P   +6 more
doaj  

Minimally invasive sacroiliac joint fusion: Primary endpoint results from the prospective, multicenter STACI study

PM&R, EarlyView.
Abstract Background Chronic sacroiliac joint (SIJ) pain is highly debilitating. Minimally invasive SIJ fusion has become a commonly performed surgical treatment for SIJ pain, with level I evidence showing clinically significant improvements in pain, function, and quality of life and a low adverse event rate.
Jacqueline Weisbein, Timothy Davis, Douglas Beall, Jack Smith, Caroline Harstroem, Daniel Kloster, Morteza Rabii, Robyn Capobianco, Ramana Naidu, Michael Harned, Christopher Mallard, the STACI investigators   +11 more
wiley   +1 more source

Significance of fiber orientation in the interosseous sacroiliac ligament: An anatomical and histological study of the implications of its mechanical adaptation

Journal of Anatomy, EarlyView.
Fiber structure of the interosseous sacroiliac ligament exhibits a distinct organization, with predominantly vertical fibers in the inferior region and predominantly horizontal fibers in the superior region. These fiber alignment patterns likely reflect mechanical adaptation to the sacroiliac joint motion and may support imaging‐based evaluation of its
Masahiro Tsutsumi, Akimoto Nimura, Hajime Utsunomiya, Takuya Ibara, Shintarou Kudo, Keiichi Akita   +5 more
wiley   +1 more source

Analgesic effects of platelet‐rich fibrin (PRF): A systematic review

Periodontology 2000, EarlyView.
Abstract Background Platelet‐rich fibrin (PRF), a second‐generation autologous platelet concentrate, has gained significant interest for its anti‐inflammatory and regenerative characteristics. While its role in tissue healing is well‐recognized, the analgesic potential of PRF remains under‐investigated.
Nathan E. Estrin, Troy B. Tran, Paras Ahmad, Nima Farshidfar, Georgios E. Romanos, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Evaluating Associations Between Ankylosing Spondylitis, Torque Teno Virus and Polymorphisms in Interleukin 6 and Vitamin D Receptor Genes

International Journal of Immunogenetics, Volume 53, Issue 2, Page 157-170, April 2026.
ABSTRACT The etiology of ankylosing spondylitis (AS) is complex and not yet fully understood. Interleukin‐6 (IL‐6), vitamin D and the vitamin D receptor (VDR) play an important role in modulating immune response, and Torque teno virus is considered a marker of immune status. This case–control study aimed to investigate the predisposition to AS. A total
Dănuț Cimponeriu, Lavinia‐Mariana Berca, Irina Radu, Mihai Toma, Remus Nica, Silvia Nica, Roxana Măciucă   +6 more
wiley   +1 more source

When Fever Defies Diagnosis: Wissler–Fanconi Syndrome as an Atypical Presentation of Adult‐Onset Still's Disease

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Adult‐onset Still's disease should be considered in young adults presenting with fever of unknown origin and inflammatory arthritis, even in the absence of rash or sore throat. Recognition of the Wissler–Fanconi variant and early ferritin testing can prevent diagnostic delay and enable prompt, effective immunosuppressive therapy.
Attaina Najeeb, Kamran Taj, Aqsa Abdul Qader, Salar Sultan, Khadija Waleed, Rahmat Gul Omarzai   +5 more
wiley   +1 more source