Results 81 to 90 of about 7,996 (251)

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma   +17 more
wiley   +1 more source

Clinical measurement of the thoracic kyphosis : A study of the intra-rater reliability in subjects with and without shoulder pain [PDF]

open access: yes, 2010
Copyright © Lewis and Valentine; licensee BioMed Central Ltd. 2010. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
Lewis, J.S., Valentine, R.E.
core   +2 more sources

Research progress in the application of single‐cell sequencing technology in rheumatic diseases

open access: yesRheumatology &Autoimmunity, Volume 5, Issue 4, Page 275-284, December 2025.
Application of single‐cell RNA sequencing (scRNA‐seq) technology in the study of the pathogenesis of rheumatic diseases. Tree of content illustration depicting the multi‐layered insights from scRNA‐seq in rheumatic diseases. The outer layer highlights key cell subsets identified by scRNA‐seq in rheumatoid arthritis, systemic lupus erythematosus ...
Xinzhe Feng   +5 more
wiley   +1 more source

Seronegative spondyloarthropathies : a review : part I: classification and differential diagnosis [PDF]

open access: yes, 1993
The seronegative spondyloarthropathies comprise a group of non-rheumatoid disorders with similar clinical, laboratory and genetic features. Recognition of new clinical features has supported the notion that they all form part of a clinical spectrum ...
Borg, Andrew A.   +2 more
core  

Exhaustion‐Resistant CD8 + T Cells in Ankylosing Spondylitis: A Proposed Three‐Axis Model

open access: yesImmunology, Volume 176, Issue 4, Page 409-420, December 2025.
Exhaustion‐resistant CD8+ T cells may sustain ankylosing spondylitis. A three‐axis model—intermittent T‐cell receptor engagement, IL‐15/CD28 co‐stimulation and maintained metabolic fitness—explains how PD‐1^high CD8+ T cells retain effector function and accumulate from gut to entheses, promoting inflammation and aberrant bone remodelling.
Xuhong Zhang   +3 more
wiley   +1 more source

Management of Cervical Spinal Fractures With Ankylosing Spondylitis by Single‐Anterior Surgery: A Case Series Report and Literature Review

open access: yesOrthopaedic Surgery, Volume 17, Issue 12, Page 3420-3431, December 2025.
We summarized cases of cervical spinal fractures accompanying ankylosing spondylitis (ASCSF) and preliminarily explored the management strategy. We found the majority of ASCSF patients with favorable cervical alignment and minimal displacement were able to achieve definite improvement of neurological function after a single‐anterior surgery ...
Qizhao Tan   +5 more
wiley   +1 more source

Popular treatment modalities in the management of sacroiliac joint dysfunction

open access: yesSouth African Journal of Physiotherapy, 2012
The treatment of sacroiliac joint (SIJ) dysfunction presents aclinical challenge for physiotherapists. The aim of this study was to investigatecurrent physiotherapy practise in the management of acute and chronic SIJdysfunction.
E.D. Watson
doaj   +1 more source

Intraoperative 3D Navigation‐Guided Resection of Enlarged Transverse Process for Treating Bertolotti Syndrome Unresponsive to Noninvasive Treatments: Case Report

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Bertolotti syndrome is a lumbosacral anomaly that induces persistent lumbar pain. This case describes 3D navigation‐guided resection of an enlarged transverse process. Sufficient decompression provided pain relief refractory to noninvasive treatments.
Jakub Jankowski   +5 more
wiley   +1 more source

Early Outcome of Percutaneous Cooled Radiofrequency Ablation in Degenerative Lumbar Facet Arthropathy and Sacroiliac Dysfunction with Associated Comorbid Illness: A Prospective Observational Study

open access: yesIndian Journal of Pain
Study Design: This was a prospective observational study. Objectives: We report clinical outcomes in a clinical study of patients treated with cooled radiofrequency ablation for chronic back pain associated with lumbar facet arthropathy with sacroiliac ...
Parvez Shamim   +2 more
doaj   +1 more source

Reactive Arthritis Unmasked by Tuberculosis: A Rare Case of Poncet's Disease With Disseminated TB in a Malnourished Young Adult

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT Poncet's disease is a rare, non‐destructive reactive arthritis that occurs in the presence of active tuberculosis (TB) without direct joint infection. It is often underrecognized in TB‐endemic regions due to its clinical overlap with septic or autoimmune arthritis.
Kanza Farhan   +5 more
wiley   +1 more source

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