Results 111 to 120 of about 12,722 (192)

ANMCO/ELAS/SIBioC Consensus Document: Biomarkers in heart failure [PDF]

, 2017
Biomarkers have dramatically impacted the way heart failure (HF) patients are evaluated and managed. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological or pathogenic processes, or ...
Aimo, Alberto, Aspromonte, Nadia, Ciaccio, Marcello, Clerico, Aldo, Di Tano, Giuseppe, Emdin, Michele, Feola, Mauro, Gulizia, Michele Massimo, Iacoviello, Massimo, Latini, Roberto, Masson, Serge, Migliardi, Marco, Misuraca, Gianfranco, Mortara, Andrea, Passino, Claudio, Valle, Roberto   +15 more
core   +1 more source

Vascular Endothelial Effects of Sacubitril/Valsartan in Heart Failure With Reduced Ejection Fraction: Randomized Controlled Trial [PDF]

BACKGROUND The mechanism of how sacubitril/valsartan improves outcomes in heart failure with reduced ejection fraction (HFrEF) is still incompletely understood.
Barthelmes, Jens, Flammer, Andreas J, Haider, Thomas, Hebeisen, Monika, Kreysing, Leonie, Nebunu, Delia, Nägele, Matthias P, Rossi, Valentina A, Ruschitzka, Frank, Sudano, Isabella   +9 more
core   +1 more source

Effect of sacubitril/valsartan on lipid metabolism in patients with chronic kidney disease combined with chronic heart failure: a retrospective study

Lipids in Health and Disease
Background and objective Dyslipidemia is significantly more common in those with concurrent chronic kidney disease (CKD) and chronic heart failure (CHF).
Manzhi Li, Ao Zhong, Yifan Tang, Jinnuo Yu, Mengmeng Wu, Karthick Kumaran Munisamy Selvam, Dong Sun   +6 more
doaj   +1 more source

Induction of ischaemic cardiomyopathy in mice without off‐target effects

Experimental Physiology, EarlyView.
Mark T. Waddingham, James T. Pearson
wiley   +1 more source

The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey [PDF]

, 2017
Bateman, Randy J, et al,
core   +2 more sources

Comparison of the effect of Sacubitril /Valsartan with Losartan and Captopril in improving right ventricular function in patients with right heart failure, a randomized clinical controlled trial [PDF]

Background: There is evidence supporting the efficacy of Sacubitril /Valsartan for improving left heart failure, but few studies have examined its effects on right ventricular (RV) dysfunction.
Hajahmadi, Marjan, Joghataie, Pegah, Pazoki, Mahboubeh, Zeinali, Elahe   +3 more
core   +2 more sources

Sacubitril/Valsartan Conundrum

Cardiology Research, 2021
openaire   +3 more sources

Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL Study)

The Journal of Clinical Hypertension
Sacubitril/valsartan, an angiotensin receptor‐neprilysin inhibitor, has demonstrated a superior blood pressure‐lowering effect compared with renin‐angiotensin system inhibitors in several clinical trials.
Koichi Yamamoto, Daisuke Yarimizu, Ayano Shimanishi, Shunsuke Eguchi, Kazuma Iekushi, Yoichi Takami, Yoichi Nozato, Kazuomi Kario, Hiromi Rakugi   +8 more
doaj   +1 more source

DEVELOPMENT OF ASSAY METHOD AND FORCED DEGRADATION STUDY OF VALSARTAN AND SACUBITRIL BY RP-HPLC IN TABLET FORMULATION [PDF]

, 2016
Objective: A stability-indicating high performance liquid chromatographic (HPLC) method was developed and validated for the estimation of combined tablet formulation of valsartan and sacubitril.Methods: Chromatographic separation was optimized by ...
Naazneen, S., Sridevi, A.
core   +1 more source

Dapagliflozin versus sacubitril–valsartan for heart failure with mildly reduced or preserved ejection fraction

Frontiers in Pharmacology
Background and aim:Heart failure with preserved ejection fraction (HFpEF) is associated with an increased risk of heart failure (HF) hospitalizations and cardiovascular death (CVD).
Ronen Arbel, Abed N. Azab, Abed N. Azab, Mansi Oberoi, Enis Aboalhasan, Artyom Star, Khaled Elhaj, Fouad Khalil, Hilmi Alnsasra, Hilmi Alnsasra   +9 more
doaj   +1 more source