Results 111 to 120 of about 15,205 (209)

Congestion, decongestion, renal function and diuretics in (ESC) heart failure

open access: yes
ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus   +2 more
wiley   +1 more source

Pharmacophore‐Based Identification and Molecular Characterization of Potent Neprilysin Inhibitors: Biochemical and Therapeutic Implications for Cardiovascular Diseases

open access: yesChemical Biology &Drug Design, Volume 107, Issue 2, February 2026.
Pharmacophore‐based virtual screening and molecular dynamics identified pentagalloylglucose and tannic acid as potent, non‐toxic neprilysin inhibitors. These natural compounds demonstrated strong binding affinity and stable interactions with the catalytic Zn2+ site, offering promising leads for cardiovascular drug development. ABSTRACT Neprilysin (NEP),
Chung‐Ting Kuo   +4 more
wiley   +1 more source

The Benefits of Sacubitril–Valsartan in Patients with Acute Myocardial Infarction: A Systematic Review and Meta-Analysis

open access: gold, 2021
Bo Xiong   +9 more
openalex   +1 more source

Mechanisms of action of sacubitril/valsartan on cardiac remodeling : a systems biology approach [PDF]

open access: yes, 2017
Sacubitril/Valsartan, proved superiority over other conventional heart failure management treatments, but its mechanisms of action remains obscure. In this study, we sought to explore the mechanistic details for Sacubitril/Valsartan in heart failure and ...
Bayés-Genís, Antoni   +7 more
core   +1 more source

Sacubitril/valsartan and isolated systolic hypertension in elderly patients: a prospective study

open access: yesИзвестия высших учебных заведений. Поволжский регион: Медицинские науки
Background. The purpose of the research is to evaluate the antihypertensive efficacy of sacubitril/valsartan 200 mg/day compared with valsartan 160 mg/day in patients with grade 1–2 isolated systolic arterial hypertension (ISAH).
A.S. Ryazanov   +3 more
doaj   +1 more source

The evolution of guideline-directed medical therapy among decompensated HFrEF patients in sacubitril/valsartan era: Medical expenses and clinical effectiveness

open access: hybrid, 2021
Huai-Wen Liang   +9 more
openalex   +1 more source

PCV100 Real-World IMPACT of Sacubitril/Valsartan on the Quality of Life of Heart Failure Patients in Portugal [PDF]

open access: bronze, 2020
Marta Afonso Nogueira   +9 more
openalex   +1 more source

Home - About - Disclaimer - Privacy