Results 111 to 120 of about 13,727 (197)

Sacubitril Does Not Exert Proarrhythmic Effects in Combination with Different Antiarrhythmic Drugs

Pharmaceuticals
Background: Previous studies suggest a direct effect of sacubitril on cardiac electrophysiology and indicate potential arrhythmic interactions between sacubitril and antiarrhythmic drugs.
Christian Ellermann, Carlo Mengel, Julian Wolfes, Felix K. Wegner, Benjamin Rath, Julia Köbe, Lars Eckardt, Gerrit Frommeyer   +7 more
doaj   +1 more source

Inibitori della neprilisina nel trattamento dell'insufficienza cardiaca : basi farmacologiche ed evidenze cliniche per l'associazione Sacubitril+Valsartan [PDF]

, 2016
Lo scompenso cardiaco è una sindrome multifattoriale nella quale un evento cronico come l'ipertensione, oppure un evento acuto come l'infarto , sono responsabili di alterazioni funzionali che impediscono al cuore di espellere sangue sufficiente da ...
PERONDI, MICHELE
core  

Role of neprilysin inhibitor combinations in hypertension: insights from hypertension and heart failure trials [PDF]

, 2017
Neprilysin is a neutral endopeptidase and its inhibition increases bioavailability of natriuretic peptides, bradykinin, and substance P, resulting in natriuretic, vasodilatatory, and anti-proliferative effects.
Bavishi, Chirag, Kadosh, Bernard, Kario, Kazuomi, Messerli, Franz H., Ruilope, Luis M.   +4 more
core  

Detection of muscular system adverse reaction signals in sacubitril/valsartan treatment combined with statins

Frontiers in Pharmacology
ObjectiveTo detect muscular system adverse reaction signals of sacubitril/valsartan treatment combined with statins (atorvastatin, rosuvastatin, simvastatin) to provide a reference for clinical administration.MethodsMultiplicative and additive models ...
Fukun Zhao, Min Luo, Yuanmin Wang, Mu Su, Fei Tang   +4 more
doaj   +1 more source

Sacubitril/Valsartan Conundrum

Cardiology Research, 2021
openaire   +3 more sources

Correction to ‘Early experience of Sacubitril–Valsartan in heart failure with reduced ejection fraction in real‐world clinical setting’

ESC Heart Failure, Volume 12, Issue 2, Page 1525-1525, April 2025.
wiley   +1 more source

Sacubitril [PDF]

, 2020
openaire   +1 more source

The effect of angiotensin receptor neprilysin inhibitor, sacubitril/valsartan, on central nervous system amyloid-β concentrations and clearance in the cynomolgus monkey [PDF]

, 2017
Bateman, Randy J, et al,
core   +2 more sources

Estrategias terapéuticas en la insuficiéncia cardíaca con función sistólica preservada: una revisión sistemática [PDF]

, 2017
Treball de Final de Grau en Medicina. Codi: MD1158. Curs acadèmic 2016-2017Antecedentes y objetivos: Más de la mitad de los pacientes diagnosticados de insuficiencia cardiaca (IC) presentan una función sistólica preservada (ICFSp), sin embargo, existe ...
Alonso Morillas, Ángela
core  

Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL Study)

The Journal of Clinical Hypertension
Sacubitril/valsartan, an angiotensin receptor‐neprilysin inhibitor, has demonstrated a superior blood pressure‐lowering effect compared with renin‐angiotensin system inhibitors in several clinical trials.
Koichi Yamamoto, Daisuke Yarimizu, Ayano Shimanishi, Shunsuke Eguchi, Kazuma Iekushi, Yoichi Takami, Yoichi Nozato, Kazuomi Kario, Hiromi Rakugi   +8 more
doaj   +1 more source