EFFECT OF SACUBITRIL/VALSARTAN ON NATRIURESIS, DIURESIS AND BLOOD PRESSURE IN HYPERTENSIVE PATIENTS
Рациональная фармакотерапия в кардиологии, 2017 Aim. To study the effect of sacubitril/valsartan compared with valsartan on natriuresis, diuresis, blood pressure (BP) and the level of biomarkers in hypertensive patients.Material and methods.
Zh. D. Kobalava +3 more
doaj +1 more source
Journal of Clinical MedicineBackground: Sacubitril/valsartan improves heart failure (HF) outcomes in patients with heart failure with reduced ejection fraction (HFrEF). However, randomized controlled trials (RCTs) in patients with heart failure and mildly reduced ejection fraction (
Sharath Kommu, Richard L. Berg
semanticscholar +1 more source
Congestion, decongestion, renal function and diuretics in (ESC) heart failure
ESC Heart Failure, Volume 12, Issue 2, Page 730-732, April 2025.
Jan Biegus +2 more
wiley +1 more source
Percutaneous Left Atrial Appendage Occlusion for Atrial Fibrillation in Cardiac Amyloidosis
Journal of Arrhythmia, Volume 42, Issue 1, February 2026.Left atrial appendage occlusion‐related outcomes in patients with amyloid cardiomyopathy. ABSTRACT Background Cardiac amyloidosis (CA) is frequently complicated by atrial fibrillation (AF), yet outcomes after left atrial appendage occlusion (LAAO) in this population remain poorly defined.
Abdul Hakim Almakadma +10 more
wiley +1 more source
Non-ischaemic cardiomyopathy, sudden death and implantable defibrillators: a review and meta-analysis [PDF]
, 2017 Objective: The recent Danish Study to Assess the Efficacy of ICDs in Patients with Non-ischemic Systolic Heart Failure on Mortality (DANISH) trial suggested that implantable cardioverter defibrillators (ICDs) do not reduce overall mortality in patients ...
Beggs, Simon A.S. +4 more
core +1 more source
Investigating operational stability and causes of cofactor release in fold type I amine transaminase
Protein Science, Volume 35, Issue 2, February 2026.Abstract Amine transaminases (ATAs) are pyridoxal phosphate (PLP) dependent biocatalysts frequently employed in chiral amine synthesis. Yields of ATA‐catalyzed reactions often suffer from low enzyme operational stability due to weak interactions between the ATA and the aminated cofactor pyridoxamine phosphate (PMP), which can leak from the active site ...
Xuebin Feng +2 more
wiley +1 more source
Role of neprilysin inhibitor combinations in hypertension: insights from hypertension and heart failure trials [PDF]
, 2017 Neprilysin is a neutral endopeptidase and its inhibition increases bioavailability of natriuretic peptides, bradykinin, and substance P, resulting in natriuretic, vasodilatatory, and anti-proliferative effects.
Bavishi, Chirag +4 more
core
ANMCO/ELAS/SIBioC Consensus Document: Biomarkers in heart failure [PDF]
, 2017 Biomarkers have dramatically impacted the way heart failure (HF) patients are evaluated and managed. A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological or pathogenic processes, or ...
Aimo, Alberto +15 more
core +1 more source
Heart failure with improved ejection fraction (HFimpEF) in patients treated with sacubitril/valsartan (SV) [PDF]
, 2022 Mingyu Kong +6 more
openalex +1 more source