Results 91 to 100 of about 3,632 (159)

Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. [PDF]

open access: yesNat Genet, 2018
Zhou W   +18 more
europepmc   +1 more source

ON BEHAVIOR OF THE SADDLEPOINT IN THE SADDLEPOINT APPROXIMATIONS

open access: yesON BEHAVIOR OF THE SADDLEPOINT IN THE SADDLEPOINT APPROXIMATIONS
In this paper we shall examine the behavior of the saddlepoint in the saddlepoint approximations for the $ M $-estimators of location. It is of use when applying a numerical method to solve an equation with respect to the saddlepoint as well as considering theoretical view of the approximations.
openaire  

A Mixed-Effects Model for Powerful Association Tests in Integrative Functional Genomics. [PDF]

open access: yesAm J Hum Genet, 2018
Su YR   +34 more
europepmc   +1 more source

Polynomially Adjusted Saddlepoint Density Approximations

open access: yes, 2013
This thesis aims at obtaining improved bona fide density estimates and approximants by means of adjustments applied to the widely used saddlepoint approximation. Said adjustments are determined by solving systems of equations resulting from a moment-matching argument.
openaire   +1 more source

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