Results 211 to 220 of about 339,294 (302)

Connectivity between the seizure onset zone and the thalamus correlates with seizure outcomes in thalamic responsive neurostimulation

Epilepsia, EarlyView.
Abstract Objective Thalamic responsive neurostimulation (RNS) is a surgical option for patients with drug‐refractory epilepsy. However, it is unclear whether thalamic connectivity with the seizure onset zone (SOZ) has a role in clinical outcomes. Here, we aim to investigate the clinical utility of the connectivity between the SOZ and the thalamus for ...
Varun R. Subramaniam, Andy Ho Wing Chan, Lara Marcuse, Madeleine Fields, Maite La Vega‐Talbott, Daniel D. Cummins, Juan A. Barcia, Hesham T. Ghonim, Lakshman Arcot Jayagopal, Yunju Im, Saadi Ghatan, Fedor Panov, Josue M. Avecillas‐Chasin   +12 more
wiley   +1 more source

sEEG‐guided responsive neurostimulation to treat neocortical epilepsy: A multicenter retrospective study of the efficacy and safety of depth electrode‐mediated neuromodulation

Epilepsia Open, EarlyView.
Abstract Objectives Pivotal trials have established the effectiveness of the Responsive Neurostimulation System (RNS® System) in treating focal epilepsy. In clinical trials, depth leads were primarily used to treat mesial temporal seizure onsets while cortical strip leads were used to treat neocortical seizure onsets.
Sina Sadeghzadeh, David A. Purger, Priya Bhanot, Noriah Johnson, Daniel A. N. Barbosa, Yuhao Huang, Jay J. Park, Ethan Schonfeld, Matthew A. Abikenari, Bhav Jain, Joshua P. Aronson, Cornelia Drees, Tiffany L. Fisher, Jason Gerrard, Tyler E. Gray, Saadi Ghatan, Kevin Hines, Barbara C. Jobst, Ioannis Karakis, Steven G. Ojemann, Imran H. Quraishi, Ahmed M. Raslan, Michael D. Sather, Christopher T. Skidmore, Jon T. Willie, Chengyuan Wu, Ji Yeoun Yoo, Kevin D. Graber, Casey H. Halpern, Vivek P. Buch, Jonathon J. Parker   +30 more
wiley   +1 more source

An intergenic "safe haven" region in Cryptococcus neoformans serotype D genomes. [PDF]

Fungal Genet Biol, 2020
Fan Y, Lin X.
europepmc   +1 more source

Development of the Human–Equine Attachment Scale

Equine Veterinary Journal, EarlyView.
Abstract Background Human–horse relationships encompass diverse roles, from companion to competition partner. The impact of such bonds informs owner decision‐making regarding horse management and veterinary care, yet standardised instruments to measure these unique bonds are limited.
Richard H. Corrigan, Marc Pierard, Emma Davies, David Marlin, Stephanie Evans, Jane M. Williams   +5 more
wiley   +1 more source

"WOOP is my safe haven": A qualitative feasibility and acceptability study of the Wish Outcome Obstacle Plan (WOOP) intervention for spouses of people living with early-stage dementia. [PDF]

Int J Geriatr Psychiatry
Mroz EL, Schwartz AE, Valeika S, Oettingen G, Marottoli R, David D, Hagaman A, Fedus D, Monin JK.   +8 more
europepmc   +1 more source

Advances in Double‐Stranded DNA Targeting Technologies

Exploration, EarlyView.
Double‐stranded DNA (dsDNA) plays a crucial role in genetic information storage and disease management, but its inherent stability limits access to internal bases. To overcome this challenge, various high‐specificity molecular targeting technologies have been developed to destabilize the DNA structure.
Zuhao Shen, Yiqun Liu, Yingjie Hao, Yifan Bo, Xiaochuan Dai, Shihui Wang, Tian Xia, Xin Su, Huiyu Liu   +8 more
wiley   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source