Results 41 to 50 of about 710,397 (289)
HTS Teologiese Studies/Theological Studies, 2019 Since the end of apartheid and the advent of democratic elections, South Africa has made great strides, but we still continue, at times, to be unable to practise sawubona. On one level, this is not surprising given our history of separateness.
Ian A. Nell, Ben Aldous
doaj +1 more source
Connecting the Missing Link: Bringing Together Global Philanthropists and Global Community Philanthropy Organizations [PDF]
, 2015 In a project begun in 2011, Synergos brought together individual philanthropists and leaders of community philanthropy organizations (CPOs) from around the world to learn about and understand the potentially transformative benefits of forming ...
Ann Graham
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Oceanography, 2023 Many cities around the world are taking steps to celebrate urban nature and move toward more sustainable living. As we progress, there is increasing focus on environmental initiatives and on intersecting with Black, Indigenous, and people of color (BIPOC) and other marginalized communities.
Rosana Pedra Nobre +3 more
openaire +1 more source
Are Aquinas and Whitehead Metaphorical and Analogical All the Way Down? [PDF]
, 2015 The paper argues from the perspective of a significant strand of interpretation of Aquinas and from insights in cognitive linguistics that a fruitful dialogue between Whitehead and Thomism needs to take into account that metaphysics and talk about God ...
Masson, Robert
core +3 more sources
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
For the Love of Land and People: An Evaluation of The Food Project as an Empowering Youth Development Program [PDF]
, 2017 For the Love of Land and People uses youth experiences to examine The Food Project, a youth development and urban agriculture organization from the Greater Boston area.
Walls, Emily
core +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
Focus on Impact, Not Intention: Moving from 'Safe' Spaces to Spaces of Acceptable Risk
The Journal of Consent-Based Performance, 2023 ‘Safe space’ isn’t an actionable tool; it is an aspiration. It is through the execution of actions that aspirations are achieved. Simply stating that a creative process or environment is a ‘safe space’ because one hopes or aspires for it to be so,
Laura Rikard, Amanda Rose Villarreal
doaj +1 more source