Results 81 to 90 of about 30,944 (219)

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu   +4 more
wiley   +1 more source

Spartan Daily, November 20, 2019 [PDF]

open access: yes, 2019
Volume 153, Issue 37https://scholarworks.sjsu.edu/spartan_daily_2019/1080/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran   +2 more
wiley   +1 more source

Relocalising the food chain: the role of creative public procurement [PDF]

open access: yes, 2002
The conventional food chain presents a challenge to sustainable development, containing hidden costs such as health bills, environmental damage and economic costs to the rural economy.
Morely, Adrian, Morgan, Kevin
core  

Biologically‐oriented alveolar ridge preservation to correct bone dehiscence at immediate implant placement

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background The purpose of the present case study is to describe the application of a modification of the Biologically‐oriented Alveolar Ridge Preservation (BARP) principles in cases of peri‐implant bone dehiscence (PIBD) due to a compromised alveolus at immediate implant placement (IIP).
Leonardo Trombelli, Tommaso Grenzi
wiley   +1 more source

Guided transpositional bone blocks in esthetic zone: Surgical technique and case report

open access: yesClinical Advances in Periodontics, EarlyView.
Abstract Background The ultimate objective of implant dentistry is to position the implant in a three‐dimensional, prosthetic‐driven location. This case highlights a guided approach for harvesting and positioning an autogenous bone block to restore a horizontal bone defect in the anterior maxilla.
Ming‐Fu Ye   +5 more
wiley   +1 more source

Comprehensive User Engagement Sites (CUES) in Philadelphia: A Constructive Proposal [PDF]

open access: yes, 2018
This paper is a study about Philadelphia’s comprehensive user engagement sites (CUESs) as the authors address and examine issues related to the upcoming implementation of a CUES while seeking solutions for its disputed questions and plans. Beginning with
Clark, Peter   +12 more
core  

Association of Pregabalin vs. Duloxetine with Cardiovascular Events: A Retrospective Cohort Study Among US Veterans With Chronic Musculoskeletal Pain

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pregabalin and duloxetine are widely prescribed non‐opioid medications for chronic musculoskeletal pain. Pregabalin may increase the risk of heart failure, and duloxetine increases heart rate and blood pressure; however, little is known about their comparative cardiovascular safety.
Sachalee Campbell   +11 more
wiley   +1 more source

Pharmacokinetic Evaluation of a Cinnamon Product on CYP2A6 Substrate Drugs: Application of a Novel Tool Involving the Nicotine Metabolite Ratio

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cinnamon (Cinnamomum spp.) is used as a culinary spice and dietary supplement. A major constituent, cinnamaldehyde, was previously shown to inactivate cytochrome P450 (CYP) 2A6 in vitro. A mechanistic static model predicted an ~5‐fold increase in the AUC of the CYP2A6 substrates nicotine and letrozole.
Aiden‐Hung P. Nguyen   +8 more
wiley   +1 more source

Spartan Daily, September 22, 1938 [PDF]

open access: yes, 1938
Volume 27, Issue 2https://scholarworks.sjsu.edu/spartandaily/2792/thumbnail ...
San Jose State University, School of Journalism and Mass Communications
core   +1 more source

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