Results 51 to 60 of about 46,262,713 (232)

Changing the Model of Maritime Navigation [PDF]

open access: yesTransNav, 2018
The paper describes a short history related to the development of maritime transport at the turn of the 20th century. A classic navigation model used since the mid-twentieth century as well as the development directions of current integrated navigation ...
Miroslaw Jurdzinski
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Soft Values in Port-city Relationships: Case of Reidi Road and Port of Tallinn [PDF]

open access: yesTransNav
Ports and cities have historically been strongly linked and developed in close association with each other. This study focuses on analysing the case of Tallinn Reidi Road.
Kristel Rauk, Ulla Tapaninen
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Safety, rescue at sea and legal access

open access: yesForced Migration Review, 2016
If it is to live up to its own values, the EU needs to step up search and rescue operations in the Mediterranean and open up legal means for access to protection in Europe in order to avoid the need for risky journeys across the Mediterranean.
Stefan Kessler
doaj  

Comprehensive quality evaluation for oysters of geographical indication from Rushan in China: Characteristic profile of nutrition and flavor components

open access: yesFood Chemistry: X
To reveal the differences in nutritional quality among diploid, triploid, and fattening oysters, nutrient and taste-contributing compounds were analyzed.
Shanqin Huo   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

2017-18 Annual Report Highlights

open access: yes
This two-paged factsheet highlights the accomplishments of Oregon Sea Grant for 2017 ...
Oregon State University. Sea Grant College Program
core   +3 more sources

Model of Optimal Collision Avoidance Manoeuvre on the Basis of Electronic Data Collection

open access: yesPromet (Zagreb), 2005
The results of the data analyses show that accidents mostlyinclude damages to the ship's hull and collisions. Generally allaccidents of ships can be divided into two basic categories.First, accidents in which measures for damage control shouldbe taken ...
Jelenko Švetak, Livij Jakomin
doaj   +1 more source

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