Results 51 to 60 of about 40,106,269 (274)

Determining Ship's Safe Speed and Best Possible Speed for Sea Voyage Legs [PDF]

open access: yesTransNav, 2016
The purpose and scope of this paper is to describe factors to consider when determining the ship's safe speed as well as the best speed for the sea voyage legs including directions related to vessel speed that are given in ColRegs, voyage orders and ...
Grzegorz Rutkowski
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Safety, rescue at sea and legal access

open access: yesForced Migration Review, 2016
If it is to live up to its own values, the EU needs to step up search and rescue operations in the Mediterranean and open up legal means for access to protection in Europe in order to avoid the need for risky journeys across the Mediterranean.
Stefan Kessler
doaj  

Ship Domain as a Safety Criterion in a Precautionary Area of Traffic Separation Scheme [PDF]

open access: yesTransNav, 2017
The ship domain is one of the criteria for navigational safety assessment. It is particularly important in restricted areas with high intensity traffic, where the criteria of closest point of approach (CPA) and time to CPA are difficult to apply.
Zbigniew Pietrzykowski, Janusz Magaj
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Changing the Model of Maritime Navigation [PDF]

open access: yesTransNav, 2018
The paper describes a short history related to the development of maritime transport at the turn of the 20th century. A classic navigation model used since the mid-twentieth century as well as the development directions of current integrated navigation ...
Miroslaw Jurdzinski
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Comprehensive quality evaluation for oysters of geographical indication from Rushan in China: Characteristic profile of nutrition and flavor components

open access: yesFood Chemistry: X
To reveal the differences in nutritional quality among diploid, triploid, and fattening oysters, nutrient and taste-contributing compounds were analyzed.
Shanqin Huo   +8 more
doaj   +1 more source

Analyzing the Factors Affecting the Safe Maritime Navigation for Training Apprentice Officers [PDF]

open access: yesTransNav, 2019
One of the primary factors that affect the safe maritime navigation is the insufficient experience and skill of an apprentice officer, which may be improved using simulation-based training by ensuring operational efficiency.
Myoungki Lee   +4 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

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