Results 171 to 180 of about 3,112,326 (355)

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce, Goknur Selen Kocak, José Verdú‐Díaz, Jorge Alonso‐Pérez, Kristl G. Claeys, Tanya Stojkovic, Gorka Fernández‐Eulate, Pascal Laforêt, Najoua Miladi, Filipe Di Pace, Cristiane Araujo Martins Moreno, Edmar Zanoteli, Conrad C. Weihl, Volker Straub, Ana Töpf, Jordi Díaz‐Manera, Sarcoglycan European Cohort Consortium, Adele D′Amico, Adolfo López de Munain, Alicia Alonso‐Jiménez, Ana Camacho‐Salas, Andrea Gangfuß, Andrés Nascimento, Anna Sarkozy, Anneke J. van der Kooi, Arturo Fraga‐Bau, Béla Melegh, Benedikt Schoser, Bjarne Udd, Blaz Koritnik, Carlos Ortez, Chiara Marini Bettolo, Chiara Panicucci, Claudia Weiss, Claudio Bruno, Claudio Semplicini, Cristina Dominguez‐González, Cristina Garrido, David Gómez‐Andrés, Edoardo Malfatti, Elena Pegoraro, Elke De Vos, Francina Munell, Gabriele Dekomien, Giacomo Pietro Comi, Giorgio Tasca, Isabelle Richard, Jan L. De Bleecker, Jana Haberlová, Jesper Helbo Storgaard, Johanna Palmio, John Vissing, Juan Carlos de Leon‐Hernández, Kinga Hadzsiev, Laura Costa‐Comellas, Lea Leonardis, Leroy ten Dam, Lidia González‐Quereda, Luca Bello, Luisa Politano, Manuela Santos, Marianne de Visser, Marie Rohlenová, Matteo Garibaldi, Michela Guglieri, Nicolas Deconinck, Nicoline Løkken, Omar Abdel‐Mannan, Pia Gallano, Roberto Fernández‐Torrón, Ulrike Schara‐Schmidt, Vincenzo Nigro, Vittoria Zangaro   +72 more
wiley   +1 more source

Identification and Validation of Antidepressant Small Molecules Using Bioinformatics and Mouse Depression Models

Drug Design, Development and Therapy
Yajun Qiao,1– 4,* Xingfang Zhang,2,5,6,* Hanxi Chen,2,5 Xinxin Liang,1– 4 Juan Guo,1,3 Qiannan Wang,2,5 Yi Ding,6 Lixin Wei,2,5 Hongtao Bi,2,4,5 Tingting Gao1,3 1School of Psychology, Chengdu Medical College, Chengdu, Sichuan, People’s ...
Qiao Y, Zhang X, Chen H, Liang X, Guo J, Wang Q, Ding Y, Wei L, Bi H, Gao T   +9 more
doaj  

The Role of TRPV1 Channel in Cosmetic Safety Evaluation. [PDF]

ACS Omega
Zhang C, Zhou Y, Wang X, Wang F.
europepmc   +1 more source

Evaluating Speeding Safety Performance Indicators in an Urban Area of a LMIC: A Case Study of Yaoundé, Cameroon.

Stephen Kome Fondzenyuy, Mobogshikeh Divine Moh, Steffel Ludivin Tezong Feudjio, Davide Shingo Usami, Luca Persia   +4 more
openalex   +2 more sources

Thin-walled abscesses and lumen-apposing metal stent drainage: a critical evaluation of safety and efficacy [PDF]

Jinyu Wu, Wen Wang
openalex   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Efficacy and safety evaluation of HyperSperm treatment in human semen samples. [PDF]

J Transl Med
Martinez-Vallejo MJ, Carrasquel-Martínez G, Artigues RN, Lattes K, Varea RL, Mas MR, Guirado SR, Ibáñez E, Gómez-Elías MD, Buffone MG.   +9 more
europepmc   +1 more source

Evaluation of Health and Environmental Safety in Food and Water Production Factories in Duhok Governorate

, 2021
Masood Abdulkareem Abdulrahman, Kherailah Kh. Bebo   +1 more
openalex   +2 more sources

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Safety evaluation of jagua (genipin-glycine) blue as a food additive. [PDF]

EFSA J
EFSA Panel on Food Additives and Flavourings (FAF), Castle L, Andreassen M, Aquilina G, Bastos ML, Boon P, Fallico B, FitzGerald R, Frutos Fernandez MJ, Grasl-Kraupp B, Gundert-Remy U, Gürtler R, Houdeau E, Kurek M, Louro H, Morales P, Passamonti S, Barat Baviera JM, Degen G, Gott D, Leblanc JC, Moldeus P, Waalkens-Berendsen I, Wölfle D, Civitella C, Mech A, Medrano-Padial C, Tard A, Zakidou P, Ruggeri L.   +29 more
europepmc   +1 more source