Results 21 to 30 of about 19,469,886 (406)

Developmental and reproductive toxicity of a recombinant protein subunit COVID-19 vaccine (ZF2001) in rats

npj Vaccines, 2023
ZF2001, a protein subunit vaccine against coronavirus disease 2019 (COVID-19), contains recombinant tandem repeat of dimeric receptor-binding domain (RBD) protein of the SARS-CoV-2 spike protein with an aluminium-based adjuvant. During the development of
Yisheng Song, Jinjin Shao, Guangbiao She, Wanqiang Lv, Guoyu Chen, Jing Liu, Lili Zhang, Chengda Zhang, Jiahong Wang, Ruiyu Tian, Lianpan Dai, George F. Gao, Enqi Huang, Lijiang Zhang   +13 more
doaj   +1 more source

Is students' qualitative feedback changing, now it is online? [PDF]

, 2010
The current state of ecological safety evaluation problem in design stage is analysed. Procedure of ecological safety estimation on the basis of index of objects danger and ecological risk is offered.Проанализирован современное состояние проблемы оценки ...
Абрамов, Ігор Борисович, Абрамова, Алла Александровна, Бойко, Тетяна Владиславівна, Соколов, Віталій Артемович, Статюха, Геннадій Олексійович   +4 more
core   +3 more sources

Points to consider for COVID-19 vaccine quality control and national lot release in Republic of Korea: focus on a viral vector platform [PDF]

Osong Public Health and Research Perspectives, 2022
Due to the global public health crisis caused by the coronavirus disease 2019 (COVID-19) pandemic, the importance of vaccine development has increased. In particular, a rapid supply of vaccines and prompt deployment of vaccination programs are essential ...
Jung Hun Ju, Naery Lee, Sun-hee Kim, Seokkee Chang, Misook Yang, Jihyun Shin, Eunjo Lee, Sunhwa Sung, Jung-Hwan Kim, Jin Tae Hong, Ho Jung Oh   +10 more
doaj   +1 more source

Preclinical Toxicity and Immunogenicity of a COVID-19 Vaccine (ZF2001) in Cynomolgus Monkeys

Vaccines, 2022
Although the new coronavirus disease 2019 (COVID-19) outbreak occurred in late 2019, it is still endemic worldwide, and has become a global public health problem.
Hongzhong Yang, Wei Pan, Guoyu Chen, Enqi Huang, Qijiong Lu, Yunxiang Chen, Ying Chen, Zhengbiao Yang, Lei Wen, Siming Zhang, Cong Xu, Wanqiang Lv, Lianpan Dai, Changwei Wu, Lijiang Zhang   +14 more
doaj   +1 more source

Towards Identifying and closing Gaps in Assurance of autonomous Road vehicleS - a collection of Technical Notes Part 1 [PDF]

, 2020
This report provides an introduction and overview of the Technical Topic Notes (TTNs) produced in the Towards Identifying and closing Gaps in Assurance of autonomous Road vehicleS (Tigars) project.
Bloomfield, R. E., Fletcher, G., Imai, K., Khlaaf, H., Kinoshit, Y., Kinoshita, S., Matsubara, Y., Popov, P. T., Ryan, P., Takeyama, M., Tsutake, Y.   +10 more
core   +5 more sources

Occurrence and health risk assessment of antimony, arsenic, barium, cadmium, chromium, nickel, and lead in fresh fruits consumed in South Korea

Applied Biological Chemistry, 2023
Although various fruits are consumed as fresh produce in South Korea, information on the concentrations of heavy metals in such fruits remains lacking despite the known toxic effects of the metals.
Jian Lee, Insun Hwang, Ye-Seul Park, Do Yup Lee   +3 more
doaj   +1 more source

Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators

BMC Complementary and Alternative Medicine, 2019
Background Doxorubicin (DOX) is a chemotherapy drug for malignant tumors. The clinical application of DOX is limited due to its dosage relative cardiotoxicity. Oxidative damage and cardiac inflammation appear to be involved in DOX-related cardiotoxicity.
Sheng Zhang, Zhen-Qiang You, Lin Yang, Li-Li Li, You-Ping Wu, Li-Qiang Gu, Yan-Fei Xin   +6 more
doaj   +1 more source

The complete chloroplast genome sequence of three medicinal species; Curcuma longa, Curcuma wenyujin, and Curcuma phaeocaulis (Zingiberaceae)

Mitochondrial DNA. Part B. Resources, 2021
Curcuma longa, C. wenyujin and C. phaeocaulis are important herbal medicine which of rhizomatous herbaceous perennial plant of the family Zingiberaceae.
Min-Kyeoung Kim, Woo Kyu Lee, Yoo Rae Choi, Jonghwan Kim, Ilhyun Kang, Juhye Kang   +5 more
doaj   +1 more source

Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway

Frontiers in Pharmacology, 2021
Ulcerative colitis (UC) is a chronic, idiopathic and relapsing inflammatory disease of the gastrointestinal tract that has a prolonged disease duration. Lindera aggregata (Sims) Kosterm.
Huimin Lai, Huimin Lai, Zhengbiao Yang, Zhaohuan Lou, Feng Li, Feng Xie, Wei Pan, Cong Xu, Lili Zhang, Sheng Zhang, Lijiang Zhang, Mincong Huang   +11 more
doaj   +1 more source

Safety Evaluation Concepts

Journal of AOAC INTERNATIONAL, 1975
Abstract The approach to safety evaluation is strongly influenced by the standard of safety to which one aspires. Practical considerations demand that realistic limits be set to the attainable assurances of freedom from anticipated hazard under actual conditions of use of a product.
openaire   +2 more sources