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Adaptive Design of Experiments for Safety Evaluation of Automated Vehicles
IEEE transactions on intelligent transportation systems (Print), 2022Automated Vehicles (AVs) need to be thoroughly evaluated in order to ensure their driving capabilities. However, comprehensive evaluations are intractable due to both time and monetary costs.
Jian Sun +4 more
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Mass spectrometry reviews (Print), 2022
Safety issues caused by pharmaceuticals have frequently occurred worldwide, posing a tremendous threat to human health. As an essential part of drug development, the toxicological analysis and safety evaluation is of great significance.
Yilin Chen +4 more
semanticscholar +1 more source
Safety issues caused by pharmaceuticals have frequently occurred worldwide, posing a tremendous threat to human health. As an essential part of drug development, the toxicological analysis and safety evaluation is of great significance.
Yilin Chen +4 more
semanticscholar +1 more source
Recent development in zebrafish model for bioactivity and safety evaluation of natural products
Critical reviews in food science and nutrition, 2021The zebrafish is a species of freshwater fish, popular in aquariums and laboratories. Several advantageous features have facilitated zebrafish to be extensively utilized as a valuable vertebrate model in the lab.
Fangjun Lin +6 more
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Enhancing dam safety evaluation using dam digital twins
Structure and Infrastructure Engineering, 2021Comprehensive evaluation of dams in a dynamic and proactive way is accepted as an effective strategy to improve dam safety. However, there is a lack of efficient and standardised approaches for managing monitoring-related information that can help to ...
Xi Zhu +4 more
semanticscholar +1 more source
2013
Before pharmaceutical products are evaluated in humans, it is essential that they undergo a rigorous safety assessment using in vitro models and studies in preclinical species. Once products progress into the clinic, additional preclinical studies are needed to support further clinical testing.
Jonathon D S, Holt, Jeremy P, Nuttall
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Before pharmaceutical products are evaluated in humans, it is essential that they undergo a rigorous safety assessment using in vitro models and studies in preclinical species. Once products progress into the clinic, additional preclinical studies are needed to support further clinical testing.
Jonathon D S, Holt, Jeremy P, Nuttall
openaire +2 more sources
Journal of Safety Research, 2005
In most countries, drivers licensing systems usually include teaching some aspects of using safety equipment (e.g., airbags and seat belts). However, there is now evidence worldwide that such education is inadequate, as indicated by, for example, the overrepresentation of young drivers who do not use seat belts.A randomized controlled study was ...
Anders, Nyberg +3 more
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In most countries, drivers licensing systems usually include teaching some aspects of using safety equipment (e.g., airbags and seat belts). However, there is now evidence worldwide that such education is inadequate, as indicated by, for example, the overrepresentation of young drivers who do not use seat belts.A randomized controlled study was ...
Anders, Nyberg +3 more
openaire +2 more sources
The Scales of Justitia: A Comprehensive Survey on Safety Evaluation of LLMs
arXiv.orgWith the rapid advancement of artificial intelligence, Large Language Models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), including content generation, human-computer interaction, machine translation, and code ...
Songyang Liu +7 more
semanticscholar +1 more source
Food and Chemical Toxicology, 1993
Esperase is a proteolytic enzyme preparation that can be used as a processing aid in the food industry. The following studies were performed to establish safety for the consumer: oral toxicity study (13 wk) in the rat; teratogenicity study in the rat; gene mutation assays in Salmonella typhimurium and mammalian cells in vitro, and chromosome aberration
R K, Hjortkjaer +6 more
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Esperase is a proteolytic enzyme preparation that can be used as a processing aid in the food industry. The following studies were performed to establish safety for the consumer: oral toxicity study (13 wk) in the rat; teratogenicity study in the rat; gene mutation assays in Salmonella typhimurium and mammalian cells in vitro, and chromosome aberration
R K, Hjortkjaer +6 more
openaire +2 more sources
Safety evaluation of tirofiban
Expert Opinion on Drug Safety, 2010Heightened platelet activity is pivotal in the thrombosis underlying acute coronary syndrome (ACS). The glycoprotein IIb/IIIa inhibitor tirofiban is a powerful platelet inhibitor with demonstrated efficacy and safety across the spectrum of ACS. Despite tirofiban's impact on the platelet compared with placebo, only an excess in minor and importantly not
Marco, Valgimigli, Matteo, Tebaldi
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MLLMGuard: A Multi-dimensional Safety Evaluation Suite for Multimodal Large Language Models
Neural Information Processing SystemsPowered by remarkable advancements in Large Language Models (LLMs), Multimodal Large Language Models (MLLMs) demonstrate impressive capabilities in manifold tasks.
Tianle Gu +12 more
semanticscholar +1 more source