Results 331 to 340 of about 19,469,886 (406)

Safety evaluation of fibermalt

Food and Chemical Toxicology, 2012
Fibermalt is a new soluble fiber food ingredient produced with the use of an alternansucrase enzyme from Leuconostoc mesenteroides expressed in a non-pathogenic strain of Escherichia coli. Fibermalt is predominantly composed of indigestible maltose alternan oligosaccharides (≥ 80%). Fibermalt was non-mutagenic in a bacterial reverse mutation test. In a
Laurie C, Dolan, Eva, Gietl, Ursula, La Cognata, Volker, Landschütze, Palma, Ann Marone, Ray A, Matulka   +5 more
openaire   +2 more sources

SafeBench: A Safety Evaluation Framework for Multimodal Large Language Models

International Journal of Computer Vision
Multimodal Large Language Models (MLLMs) are showing strong safety concerns (e.g., generating harmful outputs for users), which motivates the development of safety evaluation benchmarks.
Zonghao Ying, Aishan Liu, Siyuan Liang, Lei Huang, Jinyang Guo, Wenbo Zhou, Xianglong Liu, Dacheng Tao   +7 more
semanticscholar   +1 more source

Gaps in the Safety Evaluation of Generative AI

AAAI/ACM Conference on AI, Ethics, and Society
Generative AI systems produce a range of ethical and social risks. Evaluation of these risks is a critical step on the path to ensuring the safety of these systems.
Maribeth Rauh, Nahema Marchal, Arianna Manzini, L. Hendricks, R. Comanescu, Canfer Akbulut, Tom Stepleton, Juan Mateos-Garcia, Stevie Bergman, Jackie Kay, Conor Griffin, Ben Bariach, Iason Gabriel, Verena Rieser, William Isaac, Laura Weidinger   +15 more
semanticscholar   +1 more source

Safety evaluation of telbivudine

Expert Opinion on Drug Safety, 2010
Successful treatment of chronic hepatitis B (CHB) often requires long-term oral nucleoside/nucleotide agents which can be associated with viral resistance, patient non-compliance and adverse effects. Telbivudine is one of the more potent options available, with a 6.5- to 6.6-log copies/ml hepatitis B DNA reduction at 12 weeks in an early viral kinetic ...
Fung, J, Yuen, MF, But, DYK, Lai, CL
openaire   +4 more sources

Safety evaluation of benzophenone

Food and Chemical Toxicology, 1991
Benzophenone (FEMA No. 2134; CAS No. 119-61-9) was administered in the diet to rats at target dose levels of 20 mg/kg body weight/day for 90 days and 100 or 500 mg/kg/day for 28 days. Body weights and food consumption were measured weekly; haematology, clinical chemistry and urinalysis values were obtained at 4 wk and at the end of the study. Gross and
G A, Burdock, D H, Pence, R A, Ford
openaire   +2 more sources

S-Eval: Towards Automated and Comprehensive Safety Evaluation for Large Language Models

Proc. ACM Softw. Eng.
Generative large language models (LLMs) have revolutionized natural language processing with their transformative and emergent capabilities. However, recent evidence indicates that LLMs can produce harmful content that violates social norms, raising ...
Xiaohan Yuan, Jinfeng Li, Dongxia Wang, Yuefeng Chen, Xiaofeng Mao, Longtao Huang, Jialuo Chen, Hui Xue, Xiaoxia Liu, Wenhai Wang, Kui Ren, Jingyi Wang   +11 more
semanticscholar   +1 more source

In vivo and in vitro testing for the biological safety evaluation of biomaterials and medical devices

Biocompatibility and Performance of Medical Devices, 2020
Medical devices and the materials they are composed of need to be evaluated for their safety within the context of a risk management process. Safety issues related to toxicity can be evaluated using the ISO 10993 series of international standards for ...
W. H. Jong, J. Carraway, R. Geertsma
semanticscholar   +1 more source

A comparison of collision-based and conflict-based safety evaluation of left-turn bay extension

, 2020
There is a need to validate the results of conflict-based before-after (BA) evaluations in terms of their collision reduction estimation. This study compares the results of a collision-based and a conflict-based BA safety evaluation of left-turn bay ...
Yanyong Guo, Lai Zheng, T. Sayed
semanticscholar   +1 more source

A safety evaluation of aripiprazole in the treatment of schizophrenia

Expert Opinion on Drug Safety, 2020
Introduction Aripiprazole is a third generation antipsychotic approved by the US Food and Drug Administration (FDA) for the treatment of schizophrenia. Aripiprazole is available as oral and long-acting injectable (LAI) depot formulations, with a unique ...
Adrian Preda, Bryan Shapiro
semanticscholar   +1 more source

Safety evaluation of preservatives

International Journal of Cosmetic Science, 1997
Les conservateurs sont ajoutes aux produits cosmetiques pour augmenter leur duree de vie, en les protegeant contre une contamination microbienne qui sans cela les degraderait et exposerait le consommateur a un danger d'infection. Malgre tout, les conservateurs sont des produits chimiques biologiquement actifs qui exposent aussi le consommateur a des ...
openaire   +2 more sources