Results 341 to 350 of about 19,469,886 (406)
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Macronutrient substitutes: Safety evaluation
Regulatory Toxicology and Pharmacology, 1992Macronutrient substitutes, reduced-calorie substances used to replace organoleptic and/or functional properties of fats and sugars in the diet, may become a significant part of the diet as the trend toward lower fat and lower calorie diets continues. Procedures currently used to evaluate the safety of traditional food additives (microadditives) may be ...
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A safety evaluation of dimethyl fumarate in moderate-to-severe psoriasis
Expert Opinion on Drug Safety, 2020Introduction: Psoriasis is a chronic inflammatory disorder affecting skin, nails and joints. Systemic therapy of psoriasis is based upon several drugs which include fumaric acid esters (FAEs), initially introduced in 1959.
Radomir Reszke, J. Szepietowski
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A drug safety evaluation of risankizumab for psoriasis
Expert Opinion on Drug Safety, 2020Introduction: Risankizumab is a fully human monoclonal antibody that selectively targets interleukin (IL)-23A, interfering with the IL-23/17 axis that plays a crucial role in keratinocyte proliferation. In 2019, risankizumab was approved globally for the
Yi-Wei Huang, T. Tsai
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Challenges of safety evaluation
Journal of Ethnopharmacology, 2014Each application for authorisation of a medicinal product must be accompanied by the particulars and documents referred to in Directive 2001/83/EC on the Community code relating to medicinal products for human use. Details on the documentation needed for traditional herbal medicinal products (THMP) are given in article 16c of the above mentioned ...
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Safety Evaluation of Pesticides
Journal of the Forensic Science Society, 1975The need for safeguards against contamination by pesticides is considered. The present controls on these substances are examined, with particular reference to the Pesticides Safety Precaution Scheme and its requirements.
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Preclinical Safety Evaluation of Oncolytic Herpes Simplex Virus Type 2
Human Gene Therapy, 2019Oncolytic virotherapy is a new and safe therapeutic strategy based on the inherent cytotoxicity of oncolytic viruses and their ability to replicate and spread within tumors in a selective manner.
Yang Wang +16 more
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Safety Evaluation of Roundabouts in Georgia
Transportation Research Record, 2019U.S. roundabout growth has been significant in recent years and many published studies have documented significant safety benefits of roundabouts. However, the safety benefits for a roundabout may vary from region to region depending on many local ...
F. E. Gbologah +2 more
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Medical Laser Safety Hazard Evaluation
Health Physics, 2002Health care laser systems offer general laser hazards and additional specific concerns unique to the clinical environment. A formal laser hazard evaluation procedure provides an efficient mechanism for identifying potential laser safety hazards. This paper outlines such a medical laser hazard evaluation program and highlights the unique characteristics
Ben E, Edwards +3 more
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Anakinra for the treatment of rheumatoid arthritis: a safety evaluation
Expert Opinion on Drug Safety, 2018Introduction: The anti-interleukin-1 receptor antagonist, anakinra, was approved for the treatment of rheumatoid arthritis (RA) more than 12 years ago. However, its adverse effects are not well known.
J. Ramírez, J. Cañete
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