This study successfully developed and evaluated BDNF@RVG‐sEVs, a novel brain‐targeted nanomedicine based on hnmMSC‐derived sEVs, designed to overcome the BBB and enhance neurorestoration. By integrating RVG for enhanced brain targeting and encapsulating BDNF for potent neurorepair, our system address the key limitations of the conventional sEVs and ...
Xueting Wang +13 more
wiley +1 more source
Short-Term Efficacy of the Artificial Intelligence HeartBot II in Increasing Awareness and Knowledge of Heart Attack in Women: Protocol for a Randomized Controlled Trial With a Waitlist Control. [PDF]
Fukuoka Y +4 more
europepmc +1 more source
ABSTRACT Background Adolescents' experiences of social media are increasingly shaped by algorithmic recommendation systems that structure repeated exposure to diverse content types. However, research has focused predominantly on screen time, with limited attention to the diverse types of content encountered within curated feeds or how these experiences
Lizzy Winstone +7 more
wiley +1 more source
Plant-Microbiome Interactions in Medicinal Plants: A Synergistic Partnership for Biomass Production and Secondary Metabolite Accumulation. [PDF]
Wang E +6 more
europepmc +1 more source
ABSTRACT This study assessed human health risks associated with exposure to potentially toxic metals (PTMs) in soils and leafy vegetables cultivated in smallholder agricultural systems in Northeastern Brazil. Soil and vegetable samples were collected from 18 agricultural areas and analyzed for cadmium (Cd), chromium (Cr), copper (Cu), iron (Fe), nickel
Fernando Ferreira da Cunha Filho +5 more
wiley +1 more source
Combining Mendelian Randomization and Experimental Validation to Reveal the Causal Relationship Between Hallux Valgus and Serum Metabolites and to Identify Their Therapeutic Targets and Relevant Components. [PDF]
Li X +7 more
europepmc +1 more source
ABSTRACT AVATAR therapy (AT) works by facilitating a ‘face‐to‐face’ dialog between the person and a digital representation (avatar) of their persecutory voice. Although there is cumulative evidence of this way of working with voices, enhancing the therapeutic focus on improved confidence and a sense of control of the voices in social situations ...
Mar Rus‐Calafell +10 more
wiley +1 more source
School based prevention of children's sports injuries: a cluster randomized controlled trial integrating psychological skills training to reduce injury risk and improve emotional health. [PDF]
Fang Q, Liu J, Li M.
europepmc +1 more source
Perceived Educational Value of a Self‐Developed 3D‐Printed Pediatric Dentistry Simulator
ABSTRACT Purpose To design and assess a 3D‐printed pediatric dentistry simulator and to evaluate its perceived educational value and realism through student and expert feedback. Methods A maxillary simulator that is mountable on phantom heads was developed and produced by desktop stereolithography with single‐use inserts, enabling proximal caries ...
Michel Benyamin +11 more
wiley +1 more source
A Scoping Review of Digital Behavioral Approaches to Improve Medication Adherence in Type 2 Diabetes. [PDF]
Huang YM, Tiao PH, Shiyanbola O.
europepmc +1 more source

