Results 51 to 60 of about 560,441 (286)

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Sagittal alignment of the lumbar spine in a Turkish population

Neurosciences, 2007
OBJECTIVE: To understand the normal lumbar spine in the sagittal plane, and the range of lumbar lordosis. METHODS: This study was carried out in the Department of Anatomy, School of Medicine, Duzce University, Duzce, Turkey in the year 2005. We retrospectively reviewed T1-weighed sagittal spin-echo MRIs of the lumbar spine in 413 individuals (188 male,
Ozdemir, SENEM, Ayoglu, Ferruh, Barut, Cagatay, Is, Merih, Sevinc, Ozdemir   +4 more
openaire   +3 more sources

Arterial Spin‐Labeling MRI at the Cortical‐CSF Interface: A Novel Biomarker in Alzheimer Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background/Objective Arterial spin‐labeling (ASL) MRI can measure perfusion signal adjacent to CSF spaces and may provide information regarding CSF‐adjacent water transport physiology. We developed an automated pipeline to extract cortical‐CSF interface (IF) perfusion for comparison between Alzheimer disease (AD) and cognitively normal ...
Mona Asghariahmadabad, Pouya Metanat, Michael Thomas, Luke W. Bonham, Tyson Lam, Mehmet Kurt, Hong Nguyen, Tara Ellingson, Mauro Zucchelli, Stefano Casagranda, Quin Lu, Andreas M. Rauschecker, Leo Sugrue, Luis E. Savastano, Christopher P. Hess, Kamalini Ranasinghe, S. Andrew Josephson, Bruce L. Miller, Jennifer S. Yokoyama, Gil D. Rabinovici, Peter A. Ljubenkov, Lawren VandeVrede, Kambiz Nael   +22 more
wiley   +1 more source

Sex differences in factors affecting spinopelvic sagittal alignment and balance: a cross-sectional observational study in a Japanese community

Scientific Reports
Understanding how age and sex affect spinopelvic sagittal alignment is important for preventing the progression of adult spinal deformity and optimizing treatment. Here, we analyzed sex differences in age-related changes in spinopelvic sagittal alignment
Takaaki Nakano, Tetsushi Oyama, Kanichiro Wada, Kairo Wada, Gentaro Kumagai, Yoshiro Nitobe, Kotaro Aburakawa, Yasuyuki Ishibashi   +7 more
doaj   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Alignment Goals in Adult Spinal Deformity Surgery

Global Spine Journal
Study Design Narrative review. Objectives Adult spinal deformity (ASD) surgery has progressively transitioned from mean regional alignment targets to individualized segmental alignment goals, and from health-related quality of life (HRQL) alignment goals
Javier Pizones MD, PhD, Jeffrey Hills MD, Michael P. Kelly MD, Fatemeh Alavi MD, FRCSC, Susana Nuñez-Pereira MD, PhD, Justin S. Smith MD, Zeeshan M. Sardar MD, Lawrence G. Lenke MD, Stephen J. Lewis MD, FRCSC, Ferran Pellisé MD, PhD,   +10 more
doaj   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source

Enhancing total knee arthroplasty outcomes: the role of individualized femoral sagittal alignment in robotic-assisted surgery - A randomized controlled trial

Journal of Orthopaedic Surgery and Research
Background Optimal sagittal alignment of the femoral prosthesis is critical to the success of total knee arthroplasty (TKA). While robotic-assisted TKA can improve alignment accuracy, the efficacy of default femoral alignment versus individualized ...
Dehua Wang, Yu Ye, Xi Liang, Ke Li, Wei Huang   +4 more
doaj   +1 more source

Sagittal Realignment Following Decompression for Lumbar Spinal Stenosis in Elderly Patients: A Comprehensive EOS Imaging Analysis

Diagnostics
Background/Objectives: This study investigated whether decompression surgery for lumbar spinal stenosis can effectively improve sagittal alignment in elderly patients.
Hyung-Youl Park, Ho-Young Jung, Geon-U Kim, Se-Heon Lee, Jun-Seok Lee   +4 more
doaj   +1 more source