Results 161 to 170 of about 1,547,697 (371)
DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss
Advanced Science, EarlyView.Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim +11 more
wiley +1 more source
Articulator-related registration and analysis of sagittal condylar inclination
Acta Clinica Croatica, 2015 The purpose of this investigation was to study sagittal condylar inclination values within a uniform sample (Angle class I occlusion) using ‘articulator-related registration’ and Camper’s plane as a reference plane.
Samir Čimić +5 more
doaj
Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive‐Like Behaviors
Advanced Science, EarlyView.Chen et al. show that the endoplasmic reticulum (ER) stress sensor PERK is downregulated in prefrontal cortex (PFC) astrocytes in major depressive disorder and in chronic‐stress mouse models. In young mice, astrocyte‐specific PERK loss reduces the synaptogenic cue thrombospondin‐1 (TSP1), leading to synaptic and circuit deficits and depressive‐like ...
Kai Chen +8 more
wiley +1 more source
Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques
Advanced Science, EarlyView.Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang +12 more
wiley +1 more source
Identification of Femoral Reference Lines and Angles in Sagittal Plane (Preliminary Report) [PDF]
, 2017 Victor A. Vilensky, Skomoroshko PV
openalex +1 more source
Do patients with well-functioning total hip arthroplasty achieve typical sagittal plane hip kinematics? A proof of concept study [PDF]
, 2021 Ben Langley +7 more
openalex +1 more source
Advanced Science, EarlyView.Transplantation of medial ganglionic eminence (MGE) interneuron progenitors into APP/PS1 cortices restored the slow oscillation characteristic of Alzheimer's disease. Donor cells survived, migrated, and matured into functional GABAergic interneurons, forming synaptic connections.
Shinya Yokomizo +16 more
wiley +1 more source
P13.03: Transabdominal assessment of the mid‐sagittal plane of the fetal brain: comparison between two‐ and three‐dimensional ultrasound [PDF]
, 2012 T. Illescas +5 more
openalex +1 more source
Journal of neurosurgery. Spine, 2013 Faundez, Antonio, Le Huec, Jean Charles
openaire +3 more sources