Results 141 to 150 of about 2,134,838 (346)

Sainte parmi les saints

open access: yes, 2005
Au Maghreb, au XXIe siècle, les saints musulmans et les rituels qui leur sont associés, loin de se dissoudre dans une modernité uniformisante, continuent à réunir nombre de fidèles. À partir d’un travail de terrain de plusieurs années, à Tunis et à La Manouba, l’auteur analyse le culte contemporain d’une sainte du XIIIe siècle, Sayyda Mannûbiya.
openaire   +1 more source

Saint Petersburg – Leningrad – Saint Petersburg

open access: yesLidé města, 2009
A characteristic feature of the contemporary language of popular culture is an attempt to present Saint Petersburg in the categories of the superlative and greatness. A popular history of the city is based on a few selected events: 1. Founded in 1703 by Tsar Peter the Great who subsequently appointed himself emperor, the city gave rise to a new Russia ...
openaire   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis

open access: yesJournal of Comparative Effectiveness Research
Aim: We investigated the impact of repetitive transcranial magnetic stimulation (rTMS) for treatmentresistant depression on healthcare resource utilization as well as commercial and Medicare Fee-for-Service payer costs. Materials & methods:We conducted
Joseph J Taylor   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

La violencia de los santos en Nueva España

open access: yesBulletin du Centre d’Études Médiévales d’Auxerre, 2008
Antonio Rubial García
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

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