Results 241 to 250 of about 673,928 (344)

Controlled Release of Human Dental Pulp Stem Cell‐Derived Exosomes from Hydrogels Attenuates Temporomandibular Joint Osteoarthritis

Advanced Healthcare Materials, EarlyView.
Exosomes can reduce tissue damage in temporomandibular joint osteoarthritis (TMJOA), but rapid clearance limits their efficacy. This study encapsulates exosomes in hyaluronic acid hydrogels for controlled release. In a rat model, hydrogel‐encapsulated exosomes outperform free exosomes in preserving bone integrity and reducing tissue destruction ...
Victor Diez‐Guardia, Yajing Tian, Yunzhe Guo, Jiaying Li, Shengjie Cui, Cécile A. Dreiss, Eileen Gentleman, Xuedong Wang   +7 more
wiley   +1 more source

A patient with periumbilical hyperpigmentation and keratotic papules. [PDF]

JAAD Case Rep
Hedden M, Dugan K, Smith EH, Aria AB.
europepmc   +1 more source

Fouilles effectuées au « Château des Cars », commune de Saint-Merd-les-Oussines (Corrèze)

, 1947
Lucien Prieur, Franck Delage
openalex   +2 more sources

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

Advanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche, Ségolène Ladaigue, Giacomo Gropplero, Nicolas Zimmermann, Martin Nurmik, Irina Veith, Manh‐Louis Nguyen, Solenn Brosseau, Nicolas Poté, Pierre Mordant, Arnaud Roussel, Fathia Mami‐Chouaib, Fatima Mechta‐Grigoriou, Gérard Zalcman, Fabrice Soncin, Stéphanie Descroix, Maria Carla Parrini   +16 more
wiley   +1 more source

Impact on the prognosis with the creation of a dedicated stroke to mesenteric ischaemia. [PDF]

World J Emerg Surg
Rudondy V, Barral PA, Markarian T, Chopinet S, Barraud M, Gaudry M, Bourenne J, Nafati C, Grigoresco B, Lagier D, Rossillon A, Mege D.   +11 more
europepmc   +1 more source

Glepaglutide‐Loaded Foam for the Induction of Mucosal Healing in the Treatment of Inflammatory Bowel Disease

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Glepaglutide (GL), a GLP‐2 analog with an extended half‐life (50 h), is currently undergoing clinical trials for patients with short bowel syndrome. GL requires subcutaneous injection, which poses challenges for potential patient compliance. To address this challenge, we loaded GL into a rectal foam formulation using CO2 as a permeation enhancer to ...
Wunan Zhang, William Van den Bossche, Hafsa Yagoubi, Espoir K Kambale, Khadija Wahni, Tanya Saxena, Léo Guilbaud, Tom G. Moreels, Joris Messens, Ana Beloqui   +9 more
wiley   +1 more source

Large Language Models Could Revolutionize Health Care, but Technical Hurdles May Limit Their Applications.

J Med Internet Res
Beltramin D, Bousquet C, Tiffet T.
europepmc   +1 more source

Modeling mesenchymal stromal cell support to hematopoiesis within a novel 3D artificial marrow organoid system. [PDF]

Sci Rep
Schell B, Zhao LP, M'Sibih I, Kalogeraki M, Kergaravat C, Lereclus E, Fenaux P, Adès L, Toubert A, Espéli M, Balabanian K, Clave E, Dulphy N, Bisio V.   +13 more
europepmc   +1 more source

Reservoir‐Type Subcutaneous Implantable Devices Containing Porous Rate Controlling Membranes for Sustained Delivery of Risperidone

Advanced Healthcare Materials, EarlyView.
This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li, Andi Dian Permana, Juan Domínguez‐Robles, Muh Nur Amir, Habibie Habibie, Qonita Kurnia Anjani, Li Zhao, Natalia Moreno‐Castellanos, Ryan F Donnelly, Eneko Larrañeta   +9 more
wiley   +1 more source

Improving human papillomavirus vaccination coverage in France: a need to act but not to rush. [PDF]

Nat Commun
Thilly N, Michel M, Bruel S, Gagneux-Brunon A, Gilberg S, Banaszuk AS, Gauchet A, Giraudeau B, Mueller JE, Bocquier A.   +9 more
europepmc   +1 more source