Results 71 to 80 of about 3,193 (263)

Bones pràctiques i recursos per a la comunicació clara i el disseny legal a les administracions públiques

open access: yesRevista de Llengua i Dret - Journal of Language and Law
Aquesta nota presenta exemples pràctics de bones pràctiques en comunicació clara i disseny legal, i se centra especialment en el sector públic. S’hi analitzen projectes destacats, com ara la transformació de documents de la Diputació de Barcelona i l ...
Carlota Albanell Sais
doaj   +1 more source

Dissociating role of Bassoon in glutamatergic and dopaminergic neurons in alcohol‐related behaviour and affective state in mice

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Alcohol abuse and affective disorders are severe comorbid psychiatric diseases characterized by impaired brain synaptic transmission. The role of presynaptic scaffolding proteins coordinating presynaptic plasticity and neurotransmitter release, such as Bassoon (Bsn), in the pathogenesis of these disorders remains elusive.
Liubov S. Kalinichenko   +14 more
wiley   +1 more source

Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta‐analysis

open access: yesDiabetic Medicine, EarlyView.
Abstract Aim To evaluate the impact of anti‐islet antibody (IAb) screening on the general population and first‐degree relatives (FDRs)/high‐risk individuals and evidence‐based follow‐up modalities. Methods We performed this review through systematic searches of PubMed, EMBASE, Cochrane Library, Web of Science, ClinicalTrials.gov and International ...
Roberto Franceschi   +24 more
wiley   +1 more source

Cultivating inclusive remote workplaces: A serial mediation analysis of employee outcomes

open access: yesEuropean Management Review, EarlyView.
ABSTRACT The transformation of traditional workplace arrangements has introduced unique challenges for fostering inclusion and retaining organizational identification among remote workers. This study examines how inclusion climate influences employee outcomes in remote work settings ‐ a context that has become increasingly prevalent yet remains ...
Andri Georgiadou   +3 more
wiley   +1 more source

Paving the way for incumbents' digital transformation. A review and research agenda

open access: yesEuropean Management Review, EarlyView.
Abstract Digital transformation is reshaping the competitive landscape by forcing incumbent firms to rethink their strategies, organizational structures, and business models. While a substantial body of literature has explored digital transformation in specific sectors, focusing on various factors and organizational mechanisms, there remains a lack of ...
Anna Bastone   +3 more
wiley   +1 more source

How Have the Transformations of Supreme Audit Institutions Shaped Contemporary Public Auditing? A Professional, Process, and Stakeholder Perspective

open access: yesFinancial Accountability &Management, EarlyView.
ABSTRACT Research on Supreme Audit Institutions (SAIs) has expanded considerably in recent decades, reflecting their central role in promoting accountability and transparency in government. Based on a systematic review of 364 peer‐reviewed publications indexed in Scopus and Web of Science, this article examines how SAIs have redefined their work across
Nicolas Lagos
wiley   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

open access: yesThe FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero   +8 more
wiley   +1 more source

Integrating gepants into clinical practice for the acute treatment of migraine

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To assess the role of small‐molecule calcitonin gene–related peptide receptor antagonists (gepants) in the acute treatment of migraine, particularly in relation to triptan treatments. Background Triptans have established efficacy and are widely prescribed for the acute treatment of migraine.
Richard B. Lipton   +4 more
wiley   +1 more source

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang   +7 more
wiley   +1 more source

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