Results 111 to 120 of about 21,878 (269)

Synthesis and evaluation of hepatitis C antivirals : viral E2 glycoprotein / human CD81 receptor interaction inhibitors [PDF]

, 2008
The aim of the present work was to prepare compounds which inhibit the CD81-LEL—HCV-E2 interaction by binding to CD81-LEL. Starting point was a virtual screening using the open conformation of the LEL followed by synthesis and biological validation by ...
Holzer, Marcel
core  

Poplar miR1447 Is a Negative Regulator of Disease Resistance Through the SA‐Dependent Pathway

Plant Biotechnology Journal, EarlyView.
ABSTRACT Although microRNA1447 (miR1447) regulates poplar responses to abiotic stress and pest infestation, how miR1447 regulates poplar immunity against pathogens and its underlying molecular mechanisms remain to be elucidated. Here, we revealed that miR1447 functioned as a negative regulator of poplar disease resistance against fungal and bacterial ...
Dandan Xiao, Kaijing Rong, Tiantian Fu, Yicheng Li, Chun Wang, Ke Zhou, Ruen Yu, Xiaoqian Yang, Yuzhang Yang, Yuanyuan Wang, Yanwei Wang, Yonglin Wang   +11 more
wiley   +1 more source

Aspirin Resistance and Its Importance

Acta Medica Indonesiana, 2016
The use of salicylates (popularly known as aspirin or ASA) is well established for the secondary prevention of cardiovascular disease. However, there are reportedly a numer of patients who suffered repeat cardiovascular events despite being given aspirin
Aru W Sudoyo
doaj   +4 more sources

The BAHD Acyltransferase Gene Family: Evolutionary Dynamics, Biochemical Mechanisms, and Roles in Plant Stress Adaptation

Plant Biotechnology Journal, EarlyView.
BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Muhammad Mubashar Zafar, Qiao Fei, Abdul Razzaq, Ayesha Siddiqua, Ayesha Naveed, M. Nasir Khan, Huma Saleem, Xuefei Jiang   +7 more
wiley   +1 more source

Redundant Glycerol‐3‐Phosphate Acyltransferases Regulate Thermo‐Sensitive Genic Male Sterility in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Thermo‐sensitive genic male sterility (TGMS) lines play a pivotal role in two‐line hybrid rice breeding. However, the availability of elite TGMS germplasm remains limited, and the molecular mechanisms underlying fertility transition of TGMS lines are still poorly understood.
Siqi Cheng, Hai Zheng, Yunlu Tian, Chaolong Wang, Xiaowen Yu, Kun Dong, Jian Wang, Jiayu Lu, Keyi Chen, Xiaodong He, Kun Shao, Junwen Gao, Bowen Yao, Yang Hu, Zhenwei Xie, Ling He, Zhao Xie, Yuantao Zhu, Song Guo, Dekun Lei, Anqi Jian, Xufei Zhu, Hao Yu, Shihao Zhang, Minrui Chen, Yun Chen, Ling Jiang, Yulong Ren, Xiuping Guo, Shijia Liu, Xi Liu, Shanshan Zhu, Zhigang Zhao, Jianmin Wan   +33 more
wiley   +1 more source

Diclofenac solution (Pennsaid) in the management of osteoarthritis of the knee : Patient implications [PDF]

, 2009
Topical diclofenac sodium (pennsaid) is a non-steroidal-anti- inflammatory drug that is used to manage the recurrent pain and symptoms of osteoarthritis of the knee. Pennsaid is applied topically, absorbed cutaneously and concentrates locally at the site
Banning, M
core  

CitPH4 Confers Resistance to Citrus Canker by Activating Papain‐Like Cysteine Protease

Plant Biotechnology Journal, EarlyView.
ABSTRACT Citrus canker, a devastating disease caused by Xanthomonas citri subsp. citri (Xcc), poses a significant threat to global citrus production due to the high susceptibility of nearly all commercial citrus cultivars to it. Although transcription factor Citrus PH4 (CitPH4) is well known for regulating fruit acidity, its potential role in plant ...
Tao Yuan, Rongyan Huang, Zhihao Lu, Yujun Zhao, Jingchao Lv, Jiaxian He, Shengjie Lin, Chunyang He, Xukai Liu, Kun Yang, Jialing Fu, Juan Sun, Li Liao, Weikang Zheng, Wang Zhang, Huihui Jia, Yuantao Xu, Xia Wang, Qiang Xu, Fang Ding, Bin Hu   +20 more
wiley   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Poststreptococcal reactive arthritis: clinical course and outcome in 15 patients

The Turkish Journal of Pediatrics, 2000
Patients with Group A beta-hemolytic streptococcal infection and articular disease, who do not fulfill the modified Jones criteria for diagnosis of acute rheumatic fever (ARF), have been classified as having poststreptococcal reactive arthritis ...
G Koçak, A Imamoğlu, H E Tutar, S Atalay, S Türkay   +4 more
doaj  

Effects of intramolecular hydrogen bonding on the rates of complex formation of cobalt(2+) and zinc(2+) with substituted salicylic acids. [PDF]

, 1989
Diebler, H., Secco, F., Venturini, M.
core   +2 more sources