Results 141 to 150 of about 32,107 (304)

AAD-2004, a potent spin trapping molecule and microsomal prostaglandin E synthase-1 inhibitor, shows safety and efficacy in a mouse model of ALS [PDF]

, 2010
While free radicals and inflammation constitute major routes of neuronal injury occurring in neurodegenerative diseases, neither antioxidants nor nonsteroidal anti-inflammatory drugs (NSAIDs) have shown significant efficacy in human clinical trials.
Bok Yun, Byoung Gwag, Doo Im, Jae Lee, Jin Lee, Jin Shin, Joe Springer, Soo Byun, Sun Park, Sun Son, Woong Cho, Yong Lee, Young Lee   +12 more
core   +1 more source

Correction: Airborne signalling by methyl salicylate in plant pathogen resistance [PDF]

, 1997
Vladimir Shulaev, Paul Silverman, Ilya Raskin   +2 more
openalex   +1 more source

Obituary to analgesic nephropathy—an autopsy study [PDF]

, 2017
Background. To determine whether classic analgesic nephropathy with renal papillary and urothelial capillary sclerosis could still be detected at autopsy in the beginning of the 21st century, the present study which is similar to a previous one performed
Brunner, Felix P., Khanlari, Bettina, Mihatsch, Michael J.   +2 more
core  

Implications of Binding Mode and Active Site Flexibility for Inhibitor Potency against the Salicylate Synthase from Mycobacterium tuberculosis

, 2012
Gamma Chi, Alexandra Manos‐Turvey, P. D. T. O’Connor, Jodie M. Johnston, Genevieve L. Evans, Edward N. Baker, Richard J. Payne, J. Shaun Lott, Esther M. M. Bulloch   +8 more
openalex   +1 more source

Interleukin-2 therapy enhances salicylate oxidation by blood granulocytes [PDF]

, 1991
AL Jr Sagone, RM Husney, Triozzi Pl, J Rinehart   +3 more
openalex   +1 more source

Identification of a Lysine Residue in the NADH-Binding Site of Salicylate Hydroxylase from Pseudomonas putida S-1

, 1995
Kenzi Suzuki, Mitsuo Mizuguchi, Tomoharu Gomi, Eiji Itagaki   +3 more
openalex   +2 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, Volume 600, Issue 2, Page 251-266, January 2026.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Effects of Aspirin and/or Salicylate on Hydrolysis and Glucuronidation of Indomethacin in Rat Erythrocytes and Hepatocytes

, 2003
Makiko Shimizu, Aki Tsuyuki, Chizuru Yamamoto, Kumiko Ohta, Reiko Matsushita, Kayoko Suzuki, Yoshiaki Matsumoto, Masamichi Fukuoka   +7 more
openalex   +2 more sources

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, Volume 36, Issue 1, 2 January 2026.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Clinical and laboratory aspects of salicylate therapy [PDF]

, 1953
James I. Bruce
openalex