Results 251 to 260 of about 116,357 (311)

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

A deep representation learning model to predict response to vagus nerve stimulation. [PDF]

open access: yesNat Commun
Suresh H   +46 more
europepmc   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li   +10 more
wiley   +1 more source

Baclofen Modulates Neural Intrinsic Functional Connectivity in Treatment-Seeking Individuals With Alcohol Use Disorder. [PDF]

open access: yesAlcohol Clin Exp Res (Hoboken)
Logge WB   +5 more
europepmc   +1 more source

Severity matters: Using network analysis to explain low and high levels of persecutory beliefs. [PDF]

open access: yesSchizophr Res Cogn
Denecke S   +4 more
europepmc   +1 more source

Short-term intrinsic connectivity changes induced by cognitive exertion in healthy participants. [PDF]

open access: yesFront Neurosci
Barnden L   +4 more
europepmc   +1 more source

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