Results 31 to 40 of about 116,357 (311)

The Role of Acoustic Distance and Sociolinguistic Knowledge in Dialect Identification

open access: yesFrontiers in Psychology, 2018
Listeners are able to quite accurately distinguish between different dialects of their native language, but little is known about the process of dialect identification and the phonetic cues listeners use to identify someone’s regional origin.
Hanna Ruch
doaj   +1 more source

Alpha1-adrenergic receptor blockade in the ventral tegmental area attenuates acquisition of cocaine-induced pavlovian associative learning

open access: yesFrontiers in Behavioral Neuroscience, 2022
Activity of the alpha1-adrenergic receptor (α1-AR) in the ventral tegmental area (VTA) modulates dopaminergic activity, implying its modulatory role in the behavioral functions of the dopamine (DA) system.
Wojciech B. Solecki   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Human pupillary dilation response to deviant auditory stimuli: Effects of stimulus properties and voluntary attention

open access: yesFrontiers in Neuroscience, 2016
A unique sound that deviates from a repetitive background sound induces signature neural responses, such as mismatch negativity and novelty P3 response in electro-encephalography studies.
Hsin-I eLiao   +6 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Vulnerable Stakeholders’ Engagement: Advancing Stakeholder Theory with New Attribute and Salience Framework [PDF]

open access: yes, 2022
Stakeholder engagement is a central tenet for understanding and solving sustainability challenges. Given the existing stakeholder knowledge base and the fact that practitioners mostly focus on the engagement of high-power and salience stakeholders, the ...
Kamran Shafique   +3 more
core   +1 more source

Evaluation of 1 Hz/20 Hz bilateral rTMS effects on cognitive performance in patients with major depressive disorder using thinc-it

open access: yesBrain Stimulation, 2021
Naima Monira   +5 more
doaj   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Formal Modelling of Salience and Cognitive Load

open access: yes, 2008
Well-designed interfaces use procedural and sensory cues to increase the salience of appropriate actions and intentions. However, empirical studies suggest that cognitive load can influence the strength of procedural and sensory cues.
Curzon, P.   +7 more
core   +1 more source

Identifying and categorizing stakeholders for protected area expansion around a national park in Namibia

open access: yesEcology and Society, 2019
Protected areas and adjacent landscapes are increasingly being viewed as integrated. A more general awareness is emerging of the relevance of collectively managed landscapes for conservation and human well-being.
Lelani M. Mannetti   +3 more
doaj   +1 more source

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