Results 191 to 200 of about 116,902 (337)

NKX2‐5/LHX1 and UHRF1 Establishing a Positive Feedback Regulatory Circuitry Drives Esophageal Squamous Cell Carcinoma through Epigenetic Dysregulation

Advanced Science, Volume 12, Issue 20, May 29, 2025.
The study identifies a positive feed‐forward loop that intertwines DNA methylation regulator UHRF1 with Homeobox genes‐NKX2‐5/LHX1 via UMRs as a critical driver of ESCC. Pharmacological inhibition of UHRF1 and DNMT activity inhibits ESCC growth, which may represent a promising therapeutic approach to treat ESCC patients dependent on NKX2‐5/LHX1/UHRF1 ...
Xukun Li, Dandan Fan, Yong Li, Jian Yuan, Wanyuan Sun, Qinghao Zhu, Ling Qi, Xueling Wu, Jiahui Cai, Tongyang Gong, Ning Zhao, Jianzhong Su, Zhihua Liu, Hongyan Chen   +13 more
wiley   +1 more source

Retina-Inspired Models Enhance Visual Saliency Prediction. [PDF]

Entropy (Basel)
Shen G, Ma W, Zhai W, Lv X, Chen G, Tian Y.   +5 more
europepmc   +1 more source

Sensing of Feeling and "Kansei". Indirect Measurement of Feature Saliency in Face Processing.

, 1995
Takashi Kato, Masaomi Oda
openalex   +2 more sources

Shoreline Salients and Tombolos on the Santa Catarina coast (Brazil): description and analysis of the morphological relationships [PDF]

, 2002
Antonio Henrique da Fontoura Klein, Narbal Andriani, João Thadeu de Menezes   +2 more
openalex   +1 more source

Comparison of Large Language Model with Aphasia

Advanced Science, EarlyView.
Large language models (LLMs) answer almost all questions fluently but often inaccurately, which resembles a specific type of aphasia in humans. Using a data‐driven analysis called energy landscape analysis, this study reveals similarities in the internal information dynamics between LLMs and the brains of humans with receptive aphasia, such as Wernicke'
Takamitsu Watanabe, Katsuma Inoue, Yasuo Kuniyoshi, Kohei Nakajima, Kazuyuki Aihara   +4 more
wiley   +1 more source

Preference-independent saliency map in the mouse superior colliculus. [PDF]

Commun Biol
Wu R, Xu J, Li C, Zhang Z, Lin S, Li LY, Li YT.   +6 more
europepmc   +1 more source

Improving Attitude-Behavior Correspondence Through Exposure to Normative Support From a Salient Ingroup [PDF]

, 2002
Katherine M. White, Michael A. Hogg, Deborah J. Terry   +2 more
openalex   +1 more source

GLS1‐Mediated Redundancy in Glutamate Accelerates Arterial Calcification via Activating NMDAR/Ca2+/β‐Catenin Pathway

Advanced Science, EarlyView.
GLS1 is a novel contributor to arterial calcification. GLS1‐catalyzed glutamate exerts the promoting effects on osteogenic reprogramming in arteries. NMDAR, a glutamate receptor, is also activated and overexpressed during arterial calcification.
Ziting Zhou, Bing Dong, Dayu He, Jianshuai Ma, Yun Kong, Huijin Zhu, Chen Xie, Tiecheng Yang, Xin Zhen, Zhengzhipeng Zhang, Zhaohui He, Jinkun Cheng, Aoran Huang, Jie Chen, Ruo Wu, Huiyong Yin, Yanlian Chen, Jun Tao, Hui Huang   +18 more
wiley   +1 more source

EFCRFNet: A novel multi-scale framework for salient object detection. [PDF]

PLoS One
Peng H, Hu Y, Yu B, Zhang Z.
europepmc   +1 more source

Investor Reaction to Salient News in Closed‐End Country Funds

, 1998
Peter Klibanoff, Owen Lamont, Thierry A. Wizman   +2 more
openalex   +2 more sources