Results 281 to 290 of about 116,902 (337)

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

Advanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao, Xue Zhang, Xiao‐Juan Liu, Yi‐Ling Sun, Cui Yin, Dong‐Liang Tang, Cheng Xiao, Chunyi Zhou   +7 more
wiley   +1 more source

Edge-guided feature fusion network for RGB-T salient object detection. [PDF]

Front Neurorobot
Chen Y, Sun Z, Yan C, Zhao M.
europepmc   +1 more source

Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length

Advanced Science, EarlyView.
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li, Hanwen Zhang, Wenjun Zeng, Yilong Miao, Shaochen Sun, Yu Zhang, Bo Xiong   +6 more
wiley   +1 more source

LRNet: lightweight attention-oriented residual fusion network for light field salient object detection. [PDF]

Sci Rep
Ma S, Zhu X, Xu L, Zhou L, Chen D.
europepmc   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

Advanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin, Jianyi Ding, Jie Liu, Haoran Hu, Yashi Zhu, Meiqin Yang, Huijuan Zhou, Baoyou Huang, Tiefeng Huang, Mengjie Li, Yinyan He, Ang Li, Lingfei Han   +12 more
wiley   +1 more source

Unraveling the complexity of rat object vision requires a full convolutional network and beyond. [PDF]

Patterns (N Y)
Muratore P, Alemi A, Zoccolan D.
europepmc   +1 more source

Noble Metal Nanoparticles Anchored on Transition Metal Phosphides for Effective pH‐Universal Hydrogen Evolution

Advanced Science, EarlyView.
Seven types of noble metal‐transition metal phosphide hybrids are analyzed through theoretical calculations. Based on these theoretical results, a promising Pt‐CoP hybrid is prepared, consisting of strongly coupled Pt nanoparticles and CoP nanowires connected by robust Pt─P─Co bonds.
Hang Lei, Yifan Zhou, Zhuowen Huangfu, Liangjun Chen, Jin Cao, Xuelin Yang, Wenjie Mai, Zilong Wang   +7 more
wiley   +1 more source

Integrating deep learning with ECG, heart rate variability and demographic data for improved detection of atrial fibrillation. [PDF]

Open Heart
Rawshani A, Rawshani A, Smith G, Boren J, Bhatt DL, Börjesson M, Engdahl J, Kelly P, Louca A, Ramunddal T, Andersson E, Omerovic E, Mandalenakis Z, Gupta V.   +13 more
europepmc   +1 more source

An Ultrathin Optoelectronic Memristor with Dual‐Functional Photodetector and Optical Synapse Behaviors for Neuromorphic Vision

Advanced Electronic Materials, EarlyView.
An optoelectronic memristor based on an ultrathin periodic heterostructure is proposed. The unique structure enables the integration of multiple functionalities, including those of a photodetector, electric synapse, and optical synapse. This work provides a framework to design ultrathin, multifunctional, and energy‐efficient neuromorphic chips for ...
Lilan Zou, Junru An, Haonan Xu, Guizhen Wang, Shiwei Lin   +4 more
wiley   +1 more source