Results 31 to 40 of about 22,937 (266)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Personal or universal? Comparing listeners' replies and audio features [PDF]

open access: yesZbornik Radova Akademije Umetnosti
Can there be a "universal core" of aesthetic appreciation of musical pieces, beyond cultural, age-related, and personal differences? We explore this question by defining two audio quantifiers, encoding the information of different audio parameters ...
Mannone Maria, Costa Hamido Omar
doaj   +1 more source

Convex Optimization Method for Quantifying Image Quality Induced Saliency Variation

open access: yesIEEE Access, 2021
Visual saliency plays a significant role in image quality assessment. Image distortions cause shift of saliency from its original places. Being able to measure such distortion-included saliency variation (DSV) contributes towards the optimal use of ...
Pengfei Guo   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Explainable, interactive content‐based image retrieval

open access: yesApplied AI Letters, 2021
Quantifying the value of explanations in a human‐in‐the‐loop (HITL) system is difficult. Previous methods either measure explanation‐specific values that do not correspond to user tasks and needs or poll users on how useful they find the explanations to ...
Bhavan Vasu   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Saliency-Guided Point Cloud Compression for 3D Live Reconstruction

open access: yesMultimodal Technologies and Interaction
3D modeling and reconstruction are critical to creating immersive XR experiences, providing realistic virtual environments, objects, and interactions that increase user engagement and enable new forms of content manipulation. Today, 3D data can be easily
Pietro Ruiu   +2 more
doaj   +1 more source

Near Infrared Star Centroid Detection by Area Analysis of Multi-Scale Super Pixel Saliency Fusion Map

open access: yesTsinghua Science and Technology, 2019
The centroid location of a near infrared star always deviates from the real center due to the effects of surrounding radiation. To determine a more accurate center of a near infrared star, this paper proposes a method to detect the star’s saliency area ...
Xiaohu Yuan   +4 more
doaj   +1 more source

Supersaliency: A Novel Pipeline for Predicting Smooth Pursuit-Based Attention Improves Generalisability of Video Saliency

open access: yesIEEE Access, 2020
Predicting attention is a popular topic at the intersection of human and computer vision. However, even though most of the available video saliency data sets and models claim to target human observers' fixations, they fail to differentiate them from ...
Mikhail Startsev, Michael Dorr
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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