Results 71 to 80 of about 116,902 (337)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Remembrance of things perceived: Adding thalamocortical function to artificial neural networks

open access: yesFrontiers in Integrative Neuroscience, 2023
Recent research has illuminated the complexity and importance of the thalamocortical system but it has been difficult to identify what computational functions it performs.
Gerald E. Loeb
doaj   +1 more source

Temporal-Spatial Feature Pyramid for Video Saliency Detection [PDF]

open access: yesarXiv, 2021
Multi-level features are important for saliency detection. Better combination and use of multi-level features with time information can greatly improve the accuracy of the video saliency model. In order to fully combine multi-level features and make it serve the video saliency model, we propose a 3D fully convolutional encoder-decoder architecture for ...
arxiv  

Interplay of integrins and selectins in metastasis

open access: yesMolecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva   +2 more
wiley   +1 more source

Tuberculosis Bacteria Detection and Counting in Fluorescence Microscopy Images Using a Multi-Stage Deep Learning Pipeline

open access: yesInformation, 2022
The manual observation of sputum smears by fluorescence microscopy for the diagnosis and treatment monitoring of patients with tuberculosis (TB) is a laborious and subjective task.
Marios Zachariou   +4 more
doaj   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

« Up came the leaves » : l’antéposition des groupes prépositionnels (GP) et particules adverbiales comme marqueur de style

open access: yesE-REA, 2013
The aim of this paper is twofold: (a) to re-examine the different types of locative inversion involving prepositional phrases and adverbial particles with a focus on the syntactic rules that make such constructions possible.
Jean ALBRESPIT
doaj   +1 more source

Eight-Channel Multispectral Image Database for Saliency Prediction

open access: yesSensors, 2021
Saliency prediction is a very important and challenging task within the computer vision community. Many models exist that try to predict the salient regions on a scene from its RGB image values.
Miguel Ángel Martínez-Domingo   +2 more
doaj   +1 more source

Three Essays On Tax Salience: Market Salience and Political Salience [PDF]

open access: yes, 2011
This Article analyzes the behavioral economics literatures on how individuals understand taxation (i.e., tax salience). We evaluate how taxpayers respond to different presentations of tax prices both in their roles as market participants and as voters. We aim to combat several naïve notions about tax salience that currently exert a pernicious influence
Gamage, David, Shanske, Darien
openaire   +1 more source

UniST: Towards Unifying Saliency Transformer for Video Saliency Prediction and Detection [PDF]

open access: yesarXiv, 2023
Video saliency prediction and detection are thriving research domains that enable computers to simulate the distribution of visual attention akin to how humans perceiving dynamic scenes. While many approaches have crafted task-specific training paradigms for either video saliency prediction or video salient object detection tasks, few attention has ...
arxiv  

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