Results 81 to 90 of about 311,283 (352)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

A Three-Feature Model to Predict Colour Change Blindness

Vision, 2019
Change blindness is a striking shortcoming of our visual system which is exploited in the popular `Spot the difference’ game, as it makes us unable to notice large visual changes happening right before our eyes.
Steven Le Moan, Marius Pedersen
doaj   +1 more source

Three Essays On Tax Salience: Market Salience and Political Salience [PDF]

, 2011
This Article analyzes the behavioral economics literatures on how individuals understand taxation (i.e., tax salience). We evaluate how taxpayers respond to different presentations of tax prices both in their roles as market participants and as voters. We aim to combat several naïve notions about tax salience that currently exert a pernicious influence
Gamage, David, Shanske, Darien
openaire   +1 more source

Backtracking Spatial Pyramid Pooling (SPP)-based Image Classifier for Weakly Supervised Top-down Salient Object Detection

, 2018
Top-down saliency models produce a probability map that peaks at target locations specified by a task/goal such as object detection. They are usually trained in a fully supervised setting involving pixel-level annotations of objects.
Cholakkal, Hisham, Johnson, Jubin, Rajan, Deepu   +2 more
core   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

Hedging static saliency models to predict dynamic saliency

Signal Processing: Image Communication, 2020
Abstract In recent years, many computational models for saliency prediction have been introduced. For dynamic scenes, the existing models typically combine different feature maps extracted from spatial and temporal domains either by following generic integration strategies such as averaging or winners take all or using machine learning techniques to ...
Kavak, Yasin, Erdem, Erkut, Erdem, Aykut
openaire   +2 more sources

DISC: Deep Image Saliency Computing via Progressive Representation Learning

, 2015
Salient object detection increasingly receives attention as an important component or step in several pattern recognition and image processing tasks.
Chen, Tianshui, Li, Xuelong, Lin, Liang, Liu, Lingbo, Luo, Xiaonan   +4 more
core   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki, Satoru Noguchi, Hotake Takizawa, Yasushi Oya, Yuji Takahashi, Hirofumi Komaki, Hajime Arahata, Shinichiro Hayashi, Ichizo Nishino   +8 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source