Results 91 to 100 of about 1,142,230 (358)

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Visual Saliency Detection Based on Global Guidance Map and Background Attention

open access: yesIEEE Access
In the field of Visual Saliency Detection, accurately segmenting salient objects from images is crucial for various applications such as image editing and visual tracking.
Yanbin Peng, Mingkun Feng, Zhinian Zhai
doaj   +1 more source

Learning to Detect a Salient Object [PDF]

open access: yesIEEE Transactions on Pattern Analysis and Machine Intelligence, 2011
In this paper, we study the salient object detection problem for images. We formulate this problem as a binary labeling task where we separate the salient object from the background. We propose a set of novel features, including multiscale contrast, center-surround histogram, and color spatial distribution, to describe a salient object locally ...
Heung-Yeung Shum   +6 more
openaire   +3 more sources

Improvised Salient Object Detection and Manipulation

open access: yes, 2015
In case of salient subject recognition, computer algorithms have been heavily relied on scanning of images from top-left to bottom-right systematically and apply brute-force when attempting to locate objects of interest. Thus, the process turns out to be
Maity, Abhishek
core   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Facing salient and non-salient time sequence orientation types expressed by adverbs in English, Mandarin and Serbian

open access: yesLinguistics, 2023
This article intends to provide insight into how speakers of English, Mandarin, and Serbian perceive spatio-temporal relations expressed by specific pairs of adverbials.
Stamenković Dušan   +2 more
doaj   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

ROAD EXTRACTION FROM HIGH RESOLUTION SATELLITE IMAGES [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2012
Roads are significant objects of an infrastructure and the extraction of roads from aerial and satellite images are important for different applications such as automated map generation and change detection.
M. Özkaya
doaj   +1 more source

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