Results 111 to 120 of about 1,120,551 (376)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

Spillover and crossover effects of exposure to work‐related aggression and adversities: A dyadic diary study

open access: yesAggressive Behavior, Volume 49, Issue 1, Page 85-95, January 2023., 2023
Abstract The past two decades have produced extensive evidence on the manifold and severe outcomes for victims of aggression exposure in the workplace. However, due to the dominating individual‐centered approach, most findings miss a social network perspective.
Alexander Herrmann   +2 more
wiley   +1 more source

Salient semantics

open access: yesSynthese
AbstractSemantic features are components of concepts. In philosophy, there is a predominant focus on those features that are necessary (and jointly sufficient) for the application of a concept. Consequently, the method of cases has been the paradigm tool among philosophers, including experimental philosophers.
openaire   +2 more sources

Evaluation of an Algorithm for the Automatic Detection of Salient Frequencies in Individual tracks of Multi-track Musical Recording [PDF]

open access: yes, 2015
This paper evaluates the performance of a salient frequency detection algorithm. The algorithm calculates each FFT bin maximum as the maximum value of that bin across an audio region and identifies the FFT bin maximum peaks with the highest five deemed ...
Dewey, Christopher   +1 more
core  

Hierarchical Salient Object Detection for Assisted Grasping

open access: yes, 2017
Visual scene decomposition into semantic entities is one of the major challenges when creating a reliable object grasping system. Recently, we introduced a bottom-up hierarchical clustering approach which is able to segment objects and parts in a scene ...
Cremers, Armin Bernd   +4 more
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Statistical process control to monitor use of a web‐based autoplanning tool

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To investigate the use of statistical process control (SPC) for quality assurance of an integrated web‐based autoplanning tool, Radiation Planning Assistant (RPA). Methods Automatically generated plans were downloaded and imported into two treatment planning systems (TPSs), RayStation and Eclipse, in which they were recalculated using ...
Hunter Mehrens   +5 more
wiley   +1 more source

Semantic Instance Meets Salient Object: Study on Video Semantic Salient Instance Segmentation [PDF]

open access: yesarXiv, 2018
Focusing on only semantic instances that only salient in a scene gains more benefits for robot navigation and self-driving cars than looking at all objects in the whole scene. This paper pushes the envelope on salient regions in a video to decompose them into semantically meaningful components, namely, semantic salient instances.
arxiv  

Salient Object Detection via Augmented Hypotheses [PDF]

open access: yes, 2015
In this paper, we propose using \textit{augmented hypotheses} which consider objectness, foreground and compactness for salient object detection. Our algorithm consists of four basic steps.
Nguyen, Tam V., Sepulveda, Jose
core   +2 more sources

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

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