Results 191 to 200 of about 125,426 (353)

Isolation, Insularity and Resilience: A Review of the Geophysical, Socioeconomic, and Environmental Vulnerabilities of Gran Canaria and Lesvos Islands for Policy Interventions to Global Change

open access: yesSustainable Development, EarlyView.
ABSTRACT The dynamic nature of small islands being geographically isolated and their perceived connectedness with global networks complicates research attempts to draw general conclusions on whether insularity leads to marginalization or strengthens their resilience for sustainable development.
Toheeb Lekan Jolaosho   +2 more
wiley   +1 more source

SALINITY-Induced Changes in Diversity, Stability, and Functional Profiles of Microbial Communities in Different Saline Lakes in Arid Areas. [PDF]

open access: yesMicrob Ecol
Gao L   +10 more
europepmc   +1 more source

Nasal Delivery of mRNA Using Thermoresponsive Gellable Aqueous Biphasic Systems

open access: yesSmall, EarlyView.
Nasal delivery of mRNA using gellable aqueous biphasic systems (ABS) represents a noninvasive alternative while reducing the need for trained professionals and cold chain storage. Composed of gelatin, PEG, and water, these thermoresponsive hydrogels ensure controlled mRNA delivery and prolonged retention at the nasal mucosa, improving transfection ...
Bojan Kopilovic   +4 more
wiley   +1 more source

Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders

open access: yesSmall, EarlyView.
Little is known about the effects of polystyrene nanoplastics (PS‐NPs) on gonadotropin releasing hormone (GnRH) neurons, which control puberty onset and fertility. By applying tailored in vitro GnRH neuron models, this article shows how PS‐NPs are internalized and impact hormone secretion and cell migration, through gene expression changes. Ultimately,
Federica Amoruso   +14 more
wiley   +1 more source

Reprogramming Immunogenicity of Iron Oxide Nanoparticles through Sulfated Glycan Presentation

open access: yesSmall, EarlyView.
This study presents a comparative analysis of heparin (HP)‐ and dextran sulfate (DS)‐coated superparamagnetic iron oxide nanoparticles (SPIONs) as a tunable immunomodulatory platform where surface chemistry dictates therapeutic function. DS‐SPIONs are preferentially internalized by myeloid cells, reprogramming them into a pro‐healing M2 phenotype ...
Negin Pournoori   +8 more
wiley   +1 more source

Step‐Ladder Bioprinting to Align Collagen Fibers for Anisotropic Tissue Fabrication

open access: yesSmall, EarlyView.
The step‐ladder printing platform includes successive segments of channels with varying widths in a custom barrel design. This design allows for improved anisotropy of collagen fibers during extrusion. To demonstrate its effectiveness, corneal constructs with high transparency and shape fidelity, as well as articular cartilage constructs, displaying ...
Ilayda Namli   +8 more
wiley   +1 more source

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