Results 151 to 160 of about 8,989 (214)
Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla +15 more
wiley +1 more source
In this work, a synergistic strategy introduces interfacial acid sites, oxygen vacancies, and built‐in electric field into ZnSe/ZnO heterojunction to optimize its electronic structure and electrode micro‐environment. This overcomes sluggish oxygen reduction reaction kinetics and low H2O2 selectivity, achieving record H2O2 productivity (754.4 M gcat−1 ...
Lijun Yang +8 more
wiley +1 more source
The intimate interaction between negatively charged RNA molecules and conjugated polymers in organic electrochemical transistors (OECTs) in aqueous electrolytes is investigated. It demonstrates that RNA binding reduces the volumetric capacitance of the polymer channel, enabling the development of an ultrasensitive biosensing platform capable of ...
Hong Liu +7 more
wiley +1 more source
A hierarchical hydrogel evaporator with a thin, porous photothermal layer of fused core–shell carbon‐polymer nanospheres enables ultrafast interfacial solar evaporation with minimized heat loss and sufficient water supply. Directional advection‐dominated brine transport, coupled with Marangoni‐driven interfacial flow, drives salt away from the active ...
Haokun Shen +11 more
wiley +1 more source
Magnetic particles are organized into layered architectures by combining shear flow and magnetic fields, with the resulting structures governed by appropriate Mason numbers. The programmed assemblies provide spatial guidance for cell placement, linking field‐controlled self‐assembly, flow‐induced structuring and biological organization.
Guillermo Camacho +5 more
wiley +1 more source
Salinization and Water Logging
openaire +1 more source
Our SEA strategy provides an efficient and biosafe approach for the on‐demand removal of implanted bioresorbable materials through cascading degradation that couples ultrasound‐triggered rapid mechanical disintegration with subsequent enzymatic degradation.
Jinsong Kim +9 more
wiley +1 more source
Fully recombinant protein‐based biomaterials execute complex Boolean logic for user‐programmable material degradation and concomitant therapeutic cargo release. Biologics, such as growth factors, can be incorporated within the crosslinkers as “drugamers”, while encapsulated cells can be released according to nested YES/OR/AND‐type logical operations ...
Murial L. Ross +3 more
wiley +1 more source

