Results 131 to 140 of about 161,093 (329)

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

Advanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang, Zhengpeng Wan, Lei Wang, Caihong Wu, Junkai Zhang, Sarah Spitz, Xun Wang, Marie A. Floryan, Mark F. Coughlin, Francesca M. Pramotton, Liling Xu, Ron Weiss, Roger D. Kamm   +12 more
wiley   +1 more source

Osmotic energy harvesting from produced water and boiler blowdown water by sulfonated Poly(ether ether ketone)-based mixed matrix membranes

Advanced Membranes
The salinity gradient between produced water and boiler blowdown water – both significant waste streams in the petroleum industry – represents an emerging, clean, and sustainable energy source. This energy can be directly converted to electricity through
Li Cao, I-Chun Chen, Cailing Chen, Xiaowei Liu, Kai Qu, Zhen Li, Khalid Hazazi, Zhiping Lai   +7 more
doaj   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Copolymers of Poly(Butylene Trans‐1,4‐Cyclohexanedicarboxylate)/Pripol as New Biomaterial Platform for Small Diameter Vascular Graft

Advanced Healthcare Materials, EarlyView.
Electrospun tubular scaffolds from novel PBCE‐based copolyesters and blends were designed as candidates for small‐diameter vascular grafts. They combine defect‐free architecture, blood‐compatible surfaces, and mechanical properties comparable to native vessels.
Edoardo Bondi, Gabriele Obino, Giulia Guidotti, Alberto Sensini, Martijn van Griensven, Antonio Junior Lepedda, Nadia Lotti, Lorenzo Moroni   +7 more
wiley   +1 more source

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Unlocking osmotic energy harvesting potential in challenging real-world hypersaline environments through vermiculite-based hetero-nanochannels

Nature Communications
Nanochannel membranes have demonstrated remarkable potential for osmotic energy harvesting; however, their efficiency in practical high-salinity systems is hindered by reduced ion selectivity.
Jin Wang, Zheng Cui, Shangzhen Li, Zeyuan Song, Miaolu He, Danxi Huang, Yuan Feng, YanZheng Liu, Ke Zhou, Xudong Wang, Lei Wang   +10 more
doaj   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Reverse Electrodialysis with Continuous Random Variation in Nanochannel Shape: Salinity Gradient-Driven Power Generation

Nanomaterials
The shape of nanochannels plays a crucial role in the ion selectivity and overall performance of reverse electrodialysis (RED) systems. However, current research on two-dimensional nanochannel shapes is largely limited to a few fixed asymmetric forms ...
Runchen Zhao, Jinhui Zhou, Tianqi Bu, Hao Li, Yanmei Jiao   +4 more
doaj   +1 more source

Underwater Acoustic Detection of Ultra High Energy Neutrinos

, 2005
We investigate the acoustic detection method of 10^18-20 eV neutrinos in a Mediterranean Sea environment. The acoustic signal is re-evaluated according to dedicated cascade simulations and a complex phase dependant absorption model, and compared to ...
Aguilar, Alvarez-Muniz, Alvarez-Muniz, Anthony, Askariyan, Askariyan, Bertou, Blankenbecler, Brown, Dedenko, Feldman, Fletcher, Francois, Gandhi, Glashow, Gorham, Greisen, Greisen, Hansen, Hotta, Knudsen, Landau, Landau, Learned, Lehtinen, Liebermann, Migdal, Nagano, Smirnov, Stanev, Sulak, Urick, V. Bertin, V. Niess, Waxman, Zaptsepin   +35 more
core   +3 more sources

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

Advanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee, Yeongdo Lee, Enji Kim, Hunkyu Seo, Myoungjae Oh, Hanho Joo, Somin Lee, Jae‐Hyun Lee, Hyun Ho Jung, Minsuk Kwak, Jang‐Ung Park   +10 more
wiley   +1 more source