Results 51 to 60 of about 5,550,566 (291)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Review on reverse electrodialysis process-a pioneering technology for energy generation by salinity gradient

Frontiers in Membrane Science and Technology
Blue energy obtained by salinity gradient can be generated by mixing two saline solutions having different salt concentrations. According to researchers working in this area, about 80% of the current global electricity demand could potentially be covered
Taha Furkan Gül, Minel Akalın, Eda Nur Dönmezler, Ahmet Bolat, Aydın Cihanoğlu, Aydın Cihanoğlu, Enver Güler, Nalan Kabay   +7 more
doaj   +1 more source

Application of salinity gradient power for brines disposal and energy utilisation

Desalination and Water Treatment, 2009
Disposal of high saline brines is a common and important problem in many industrial plants. These waste streams may be generated in large volumes in many different industries. It is well known that these concentrated brines cannot be desalted by using the conventional desalination technologies due to two crucial factors which are; cost and reliability.
M. Ahmad, P. Williams
openaire   +3 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Improved Rectification and Osmotic Power in Polyelectrolyte-Filled Mesopores

Micromachines, 2020
Ample studies have shown the use of nanofluidics in the ionic diode and osmotic power generation, but similar ionic devices performed with large-sized mesopores are still poorly understood.
Ding-Cheng Zheng, Li-Hsien Yeh
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Reverse electrodialysis for salinity gradient power generation

Journal of Membrane Science & Research, 2018
Salinity gradient energy, which is also known as Blue energy, is a renewable energy form that can be extracted from the mixing of two solutions with different salinities. About 80% of the current global electricity demand could potentially be covered by this energy source.
Güler, Enver, Nijmeijer, Kitty
openaire   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Pressure Retarded Osmosis Power Units Modelling for Power Flow Analysis of Electric Distribution Networks

Energies, 2021
Pressure retarded osmosis (PRO) power units, which produce electrical energy from salinity gradient sources located at coastlines, are a technology still in the process of maturation; however, there is an expectation that this technology will need to be ...
Mario Llamas-Rivas, Alejandro Pizano-Martínez, Claudio R. Fuerte-Esquivel, Luis R. Merchan-Villalba, José M. Lozano-García, Enrique A. Zamora-Cárdenas, Víctor J. Gutiérrez-Martínez   +6 more
doaj   +1 more source