Results 131 to 140 of about 1,533,392 (296)

Saliva sample for testing SARS-CoV-2 infection, 1st update on diagnostic accuracy [PDF]

open access: yes, 2020
Key messages The aim of this review was to investigate the diagnostic accuracy of reverse transcription real time polymerase chain reaction (rRT-PCR) for detection of SARS-CoV2 in saliva specimens compared to upper airway samples.
Lauvrak, Vigdis, Juvet, Lene Kristine
core  

PIAS3 CircRNA‐Loaded Lipid Nanoparticles Restore ALOX15 SUMOylation to Suppress Cementoblast Ferroptosis and Attenuate Orthodontically Induced Root Resorption

open access: yesAdvanced Science, EarlyView.
Orthodontic compression suppresses PIAS3 expression in cementoblasts, impairing ALOX15 SUMOylation and ubiquitin‐mediated degradation, which leads to ALOX15 accumulation, lipid peroxidation, ferroptosis, and osteoclastogenesis. Local delivery of PIAS3 circRNA‐loaded lipid nanoparticles restores the PIAS3–ALOX15 regulatory pathway, alleviates ...
Yifei Hou   +11 more
wiley   +1 more source

Salivary Citrate Deficiency Defines an Endogenous Dentin Remineralization Failure State Through Glandular MT1/2‐Zn2+‐ACO2 Dysregulation

open access: yesAdvanced Science, EarlyView.
Salivary citrate deficiency in early‐stage Sjögren's syndrome accompanies impaired dentin remineralization despite preserved salivary flow and mineral availability. Matched‐ion experiments reveal disrupted mineral organization and reduced dentin recovery at disease‐associated citrate levels.
Ran You   +8 more
wiley   +1 more source

Antioxidant capacity of human saliva and periodontal screening assessment in healthy adults

open access: yes, 2017
OBJECTIVE: Saliva plays a pivotal role as an antioxidant system, and saliva antioxidant levels are reduced in patients with periodontal disease. Recently, a biochemical test able to determine saliva antioxidant levels was proposed as predictive for ...
Nicoletta Gagliano   +9 more
core   +1 more source

Spray‐Dried mRNA‐LNP Powder Enabling Multi‐Route Delivery With 3‐Year Refrigerated Stability

open access: yesAdvanced Science, EarlyView.
Spray‐dried mRNA‐LNP powder with trehalose matrix enables reconstitution for parenteral delivery or direct administration via pulmonary and sublingual routes, maintaining protein expression comparable to liquid controls. The thermostable powder preserves colloidal stability, mRNA integrity, and biological activity for over 3 years at 2°C–8°C, while ...
Ashish Sarode   +4 more
wiley   +1 more source

[Health promotion strategy 2004] / Irish Cervical Screening Programme

open access: yes, 2004
Irish Cervical Screening ...
Irish Cervical Screening Programme (ICSP)
core  

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

open access: yesAdvanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler   +4 more
wiley   +1 more source

13 Saliva for newborn screening for CF

open access: yesJournal of Cystic Fibrosis, 2017
A.C. Goncalves   +7 more
openaire   +1 more source

A Single Volatile VO2 Memristor Enabling Neuromorphic Perception, Learning, and Computing

open access: yesAdvanced Electronic Materials, EarlyView.
A single volatile VO2 memristor fabricated via atomic layer deposition is demonstrated as a multifunctional neuromorphic device enabled by intrinsic threshold‐switching dynamics. The device reproduces neuron‐like integration and firing, short‐timescale associative learning, temporal ECG pattern classification, and nociceptive responses to electrical ...
Bingkai Ding   +7 more
wiley   +1 more source

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