Results 61 to 70 of about 1,533,392 (296)
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Toukeibu Gan, 2008 我々は簡便で非侵襲的に反復して採取できる全唾液を試料とした口腔癌のスクリーニング検査の開発を行ってきた。今回，二次元電気泳動法，peptide-mass fingerprinting法によって口腔癌の全唾液で特徴的に変化するバイオマーカーの同定を行った。その結果，口腔癌患者の術前全唾液から検出され，術後全唾液および健常者全唾液から検出されない口腔扁平上皮癌と関係のあると考えられるタンパク質スポットは10個であった。その中で，口腔癌患者の唾液のみで検出されるenolase 1が同定された。enolase 1は口腔扁平上皮癌組織では健常組織に比べて強く発現していることが，免疫組織化学染色で確認された。このことから，enolase 1は唾液中に出現する口腔癌のバイオマーカーとしての有用性が示唆され ...
Katakura, Akira +9 more
openaire +2 more sources
Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro +6 more
wiley +1 more source
Erosion protection conferred by whole human saliva, dialysed saliva, and artificial saliva. [PDF]
, 2016 During dental erosion, tooth minerals are dissolved, leading to a softening of the surface and consequently to irreversible surface loss. Components from human saliva form a pellicle on the tooth surface, providing some protection against erosion.
Baumann, Tommy +3 more
core +2 more sources
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
Scientific Reports, 2022 Without any realistic prospect of comprehensive global vaccine coverage and lasting immunity, control of pandemics such as COVID-19 will require implementation of large-scale, rapid identification and isolation of infectious individuals to limit further ...
Robert E. Dewhurst +9 more
doaj +1 more source
Mass screening of asymptomatic persons for SARS-CoV-2 using saliva [PDF]
, 2020 Abstract Background COVID-19 has rapidly evolved to become a global pandemic due largely to the transmission of its causative virus through asymptomatic carriers. Detection of SARS-CoV-2 in asymptomatic people is an urgent priority for the prevention and containment of disease outbreaks in ...
Isao Yokota +12 more
openaire +1 more source
The Gut–Heart Axis in Systemic Sclerosis: Evidence From a Large Prospective Early Disease Cohort
Arthritis Care &Research, EarlyView.Objective Cardiac involvement significantly impacts prognosis in systemic sclerosis (SSc), highlighting the need for early risk stratification. Gastrointestinal (GI) symptoms are common and often manifest early. Emerging data suggest a link between GI and cardiac manifestations, possibly through shared mechanisms like dysautonomia.
Francesca R. Di Ciommo +9 more
wiley +1 more source
Disposable screen printed sensor for the electrochemical detection of methamphetamine in undiluted saliva [PDF]
Chemistry Central Journal, 2016 Methamphetamine has an adverse effect on the ability to drive safely. Police need to quickly screen potentially impaired drivers therefore a rapid disposable test for methamphetamine is highly desirable. This is the first proof-of-concept report of a disposable electrochemical test for methamphetamine in undiluted saliva.A screen printed carbon ...
Bartlett, Carrie-Ann +8 more
openaire +3 more sources